ALSPAC has collected neuroimaging data on ~900 G1 participants (original children) acquired at sub studies between 18-24 years of age. Variables derived from these studies can be found in this documentation: MRI variables (PDF, 7,002kB).

The scan data is also available on request (subject to a cost recovery fee). This includes acquisition of structural, functional and magnetization transfer magnetic resonance, diffusion tensor, and magnetoencephalography imaging. The resource provides a unique opportunity to combine neuroimaging data with extensive phenotypic and genotypic measures from participants, their mothers, and fathers.

Data Description

A full description of this resource and how it is structured can be found here: 'Population neuroimaging: generation of a comprehensive data resource within the ALSPAC pregnancy and birth cohort.' by Sharp TH, McBride NS, Howell AE et al. Wellcome Open Res 2020, 5:203 (https://doi.org/10.12688/wellcomeopenres.16060.1)

 

 

‌Flow chart depicting the sampling of each neuroimaging sub-study within ALSPAC, modalities acquired, and processing pipeline of structural MRIs.

 

Scan types available:

Study	Structural (T1)	Functional (fMRI)	Diffusion Tensor (DTI/DWI)	Relaxometry (mcDESPOT)
Testosterone Study (Paus)	504	474	500	489
PE Study (David)	252	214	249	248
SCZ-RbG Study (Linden)	196	190 / 192*	191	183

For the SCZ-
RbG Study/Linden, two different functional MRI tasks were done (N-Back and Reversal learning tasks) 

Any enquiries please contact: alspac-data@bristol.ac.uk.