Spinning disk

The Wolfson Bioimaging Facility offers spinning disk microscopy as an alternative form of confocal imaging.

Our Olympus IXplore SpinSR system incorporates Yokogawa CSU-W1 SoRa spinning disk and enables super-resolution imaging.

Spinning disk microscopes offer an approach to confocal imaging which differs from more commonly used CLSM systems. In spinning disk systems, image detection by a camera is restricted to a single focal plane by an array of pinholes in a rapidly spinning disk which also distributes laser excitation across a field of view. Improved acquisition speed and lower peak power can offer advantages over CLSM systems for live imaging applications.

Olympus SpinSR technical specifications (PDF, 166kB)

Advice with Large file handling (PDF, 88kB)

Recent papers:

Needs, Glover, Pereira, Witt, Hübner, Dodding, Henley, Collinson. (2024) Rescue of mitochondrial import failure by intercellular organellar transfer. Nature Communications 15(1):988.

Daly, Danson, Lewis, Zhao, Riccardo, Di Filippo, Cacchiarelli, Lee, Cross, Heesom, Xiong, Ballabio, Edgar, Cullen. (2023) Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health (2023) Nature Communications 14(1):3086.

Lu, Veler, Simonetti, Raj, Chou, Cross, Phillips, Ruan, Huynh, Dowsey, Ye, Murphy, Verkade, Cullen, Wülfing (2023) Five inhibitory receptors display distinct vesicular distributions in murine T cells. Cells 12(21):2558


More information and access

For further information or to arrange access to this equipment, contact one of the team.

We welcome comments or suggestions. Please contact one of the team or one of the advisory group.

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