We use both spatially-specific and electrophysiological imaging methods in our research projects. Advanced structural Magnetic Resonance Imaging (sMRI) is developed to understand brain changes in normal ageing and in people with memory and cognitive decline. Functional MRI (fMRI) is used, in combination with psychological measures, to study neural underpinnings how we perceive and evaluate strangers at network level.
EEG and evoked responses are recorded in studies on language processing and conscious perception. EEG recordings are also used to investigate sensory and semantic processing in ageing and cognitive impairment.
We have shown using state-of-the-art imaging combined with causal modelling that damage in white matter appears to cause subsequent damage in grey matter. This should be important in trying to treat such problems as Alzheimer's.
Funding grant: MRC (2018-2023) Glucocorticoid dynamics in health and disease, £1,848,000, Lightman, Harmer, Robinson, Conway-Campbell, Gilchrist and Rivers