Mendelian Randomization

Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since its first proposal in 2003, academics working in the MRC Integrative Epidemiology Unit (IEU) and throughout Population Health Sciences at the University of Bristol Medical School (including those who are tutors on this course) have been at the forefront of developing methods for assessing and limiting potential biases with this approach.

Dates 20 - 23 February 2024
Fee £770
Format Online
Audience Open to all applicants (prerequisites apply)

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This course aims to provide an introduction to the conduct, assumptions, strengths and limitations of Mendelian randomization, including the use of up-to-date methods for sensitivity analyses that explore likely violation of Mendelian randomization assumptions.

Please click on the sections below for more information. 

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I think the teaching was excellent and engaging and the content was well paced. Ideas were repeated throughout which really helped to consolidate learning. Also I think there was an especially friendly and personable team of moderators which created a nice atmosphere.

Course feedback, February 2024

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Find out about the self-paced Materials & Recordings version of this course [UoB only].

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