Our Olympus IXplore SpinSR system incorporates Yokogawa CSU-W1 SoRa spinning disk and enables super-resolution imaging.

Spinning disk microscopes offer an approach to confocal imaging which differs from more commonly used CLSM systems. In spinning disk systems, image detection by a camera is restricted to a single focal plane by an array of pinholes in a rapidly spinning disk which also distributes laser excitation across a field of view. Improved acquisition speed and lower peak power can offer advantages over CLSM systems for live imaging applications.

Olympus SpinSR technical specifications (PDF, 166kB)

Recent papers:

Needs, Glover, Pereira, Witt, Hübner, Dodding, Henley, Collinson. (2024) Rescue of mitochondrial import failure by intercellular organellar transfer. Nature Communications 15(1):988.

Daly, Danson, Lewis, Zhao, Riccardo, Di Filippo, Cacchiarelli, Lee, Cross, Heesom, Xiong, Ballabio, Edgar, Cullen. (2023) Multi-omic approach characterises the neuroprotective role of retromer in regulating lysosomal health (2023) Nature Communications 14(1):3086.

Lu, Veler, Simonetti, Raj, Chou, Cross, Phillips, Ruan, Huynh, Dowsey, Ye, Murphy, Verkade, Cullen, Wülfing (2023) Five inhibitory receptors display distinct vesicular distributions in murine T cells. Cells 12(21):2558

‌

‌