Skin and allergy

The diagnosis and management of skin (dermatological) and allergy problems commonly seen in primary care is an established research theme at the Centre for Academic Primary Care (CAPC) and is the focus of the newly opened Centre for Applied Excellence in Skin and Allergy Research (CAESAR).

Led by Professor Matthew Ridd, CAESAR is supported by a National Institute for Health and Care Research (NIHR) Research Professorship award to build capacity and accelerate progress in answering questions of importance to patients with skin and/or allergy problems.

Working with key partners in secondary care (Centre for Evidence Based Dermatology, University of Nottingham; UK Dermatology Controlled Trials Network) and primary care (Primary Care and Population Sciences, University of Southampton), our work spans from large, flagship clinical trials through to methods work and small student projects.

Team members

Current projects

  • Trial of IGe tests for Eczema Relief (TIGER). Ridd MJ, Santer M, Blakeman T, MacNeill S, Coast J, Garfield K, Muller I, Boyle R, Meyer R, Skypala I, Dawson S, Morgans H, Brown S, Williams H. Funder: NIHR Health Technology Assessment (HTA) (2022-2025)


  • AmiTriptyline for the prevention of post-HErpetic NeuralgiA (ATHENA): multi-centre, individually randomised, pragmatic, placebo-controlled superiority trial with internal pilot study within a trial and nestted qualitative study. Ridd MJ, Pickering A, Johnson R, Fodor I, Wylde V, Kandiyali R, Heawood A, Hay AD, van Hecke O, Everitt H, Hunt L, Clayton J, MacNeill S. Funder: NIHR Health Technology Assessment Programme (2021-2024)




  • A systematic review to map and identify written action plans: where and how have written action plans for atopic eczema/dermatitis been developed and evaluated? Singh Tahndi C, Ridd M, Vincent R. This work is being done as part of a Dr Singh Thandi's Academic Clinical Fellowship.
  • RAPID and Efficient Eczema Trials (RAPID). Thomas K, Roberts A, Ridd MJ, Santer M, Muller I, Cowdell F, Bradshaw L, Tanaka R, Collins S, Haines R, Montgomery A, Mitchell E, Ravenscroft J, Williams HC. Funder: National Institute for Health and Care Research (September 2022-February 2027)

Completed projects

  • Food allergy and atopic eczema: optimising care for individual patients – Trial of IgE tests for Eczema Relief: Consensus on Using skin prick tests Best (TIGER CUB). Brown S, Ridd MJ, Boyle R, Meyer R, Skypala I. Funder: Rosetrees Trust and Stoneygate Trust, (2022-2023)
  • Eczema Care Online (ECO): Supporting self-care for eczema in the community. Santer M, Thomas K T, Muller I, Ridd M, Chalmers J, Lawton S, Stuart B, Griffiths G, Sach T, Langan, Roberts A, Ahmed A, Kirk H, Yardley L, Little P, Williams H. NIHR Programme Grant (September 2017-February 2023)
  • Should a proxy “worst itch” question be included as a core outcome in trials of treatments for childhood eczema? Guan X, MacNeill S, Ridd M J. MSc project.
  • Should pain be included in the Patient Orientated Eczema Measure? Huang A, MacNeill, Ridd M J. MSc project.
  • Best Emollient in Eczema (BEE): Pragmatic, primary care, multi-centre, individually randomised superiority trial of four emollients in children with eczema, with internal pilot and nested qualitative study. Ridd M, Santer M, Thomas K, MacNeill S, Heawood A, Banks J, Roberts A, Garfield K, Baxter H, Barrett T, Lane A, Williams H, Hay A. Funder: NIHR Health Technology Assessment (May 2017-December 2020)
  • TEST (Trial of Eczema allergy Screening Tests): feasibility randomised controlled trial with economic scoping and nested qualitative study. Ridd M, Santer M, Boyle R, Chalmers J, Blair P, Heawood A, Selman L, Coast J, Garfield K, Marriage D, Waddell L, Muller I, Kai J. Funder: NIHR School for Primary Care Research (October 2017-November 2019)
  • Action PlAns for CHildren with Eczema (APACHE): A study to develop written action plans for children with eczema and explore how best to evaluate them. Ridd M, Salisbury C, Purdy S, Metcalfe C, Heawood A, Malpass A and Waldecker A. (January 2015-December 2019)
  • Eczema and allergy engagement. Gilbertson A, Ridd M, Dawson S, Clayton J, Roberts A. Funder: NIHR School for Primary Care Research (April 2020 to March 2021).

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