Analysis finds four repurposed antiviral drugs have little or no effect on patients hospitalised for COVID-194 December 2020Repurposed antiviral drugs - remdesivir, hydroxychloroquine, lopinavir and interferon - to treat COVID-19 appear to have little or no effect on patients hospitalised for the disease, in terms of overall mortality, initiation of ventilation and duration of hospital stay. The interim findings from the WHO Solidarity trial, published in the New England Journal of Medicine (NEJM), followed 11,266 adults at 405 hospitals in 30 countries.
Treatment for drug addiction - how do patients cope in lockdown?27 November 2020There are encouraging signs that people in treatment for drug addiction can manage their medication when they are entrusted with a substantial quantity of opiate substitutes and told to take it in small daily doses, finds a new ‘early insight’ report from researchers at the Universities of Bristol and Bath.
Exceptional challenges of bereavement during the pandemic highlighted in interim findings27 November 2020Interim findings of a survey of people bereaved in the UK since March, led by researchers from the univerities of Bristol and Cardiff and the Marie Curie Palliative Care Research Centre, show the difficulties and distress experienced by those who have lost a loved one, both prior to the death and in their grief.
World's first research programme to identify scarring gene launched26 November 2020A world-leading £1.5 million research programme that aims to achieve scar free healing within a generation has been launched today [26 November] by The Scar Free Foundation, the only medical research charity which focuses solely on scarring. The five-year research study led by the University of Bristol will identify the gene(s) that causes scarring and inform future treatments.
Spread Germ Defence, not the virus!25 November 2020With Covid-19 infections still high and people preparing for Christmas gatherings, it is vitally important to try to reduce the spread of infection in people's homes as this is where infections are now most likely to be transmitted. Research suggests people who follow the advice from Germ Defence are less likely to catch flu or other viruses and less likely to pass it on to members of their household.
Young people's anxiety levels doubled during first COVID-19 lockdown, says study 24 November 2020The number of young people with anxiety doubled from 13 per cent to 24 per cent, during the early stages of the COVID-19 pandemic and lockdown 1, according to new research from the University of Bristol. The study, using Bristol’s Children of the 90s questionnaire data, showed that young people (27-29 years) reported higher levels of anxiety during the early phases of the pandemic in the first national lockdown and this was higher than their parents.
Biofriendly protocells pump up blood vessels 20 November 2020An international team of researchers from Bristol and China has prepared biocompatible protocells that generate nitric oxide gas – a known reagent for blood vessel dilation - that when placed inside blood vessels expand the biological tissue.
Bristol secures £45M to advance gene therapy treatment of chronic kidney diseases19 November 2020The University of Bristol has secured a £45million deal to advance its groundbreaking gene therapy technology for chronic kidney diseases. The commitment, made by healthcare company Syncona Ltd to Bristol spin-out Purespring Therapeutics, aims to address a global unmet need for renal conditions in one of the largest single investments made to a new UK university biotech company.
Campaign launched to help older people leave hospital when ready17 November 2020A new campaign to support older people with frailty admitted to hospital in an emergency has launched today. Many people worry about the possibility of an emergency hospital admission, and the coronavirus pandemic will be heightening these concerns. The 'Information About Me' campaign helps older patients – or their relatives or carers – give the right information about their usual day-to-day life to staff to help patients leave hospital at the right time.
Dr Colin J Mapes, 1938-2020 17 November 2020Dr Colin Mapes, former lecturer in Biological Sciences at Bristol, has died. Sir Brian Follett FRS and several colleagues offer a remembrance.
Rapid point-of-care testing during and after COVID-19 – how widely should it be used?17 November 2020Even before the COVID-19 pandemic, the point-of-care testing industry was investing millions of pounds to develop rapid tests to tell us the cause of respiratory infections. The pandemic has accelerated this process. In an editorial published in the British Journal of General Practice today [17 November], researchers from the University of Bristol’s Centre for Academic Primary Care ask if we know enough about these tests to merit their widespread use in primary care.
Accuracy of rapid covid test may be lower than previously suggested12 November 2020The accuracy of a rapid finger-prick antibody test for SARS-CoV-2, the virus responsible for Covid-19 infection, may be considerably lower than previously suggested, finds a study led by scientists from Public Health England and the Universities of Bristol, Cambridge and Warwick published in The BMJ.
Combined intimate partner violence that includes sexual violence is common and more damaging12 November 2020Women who experience sexual violence combined with other forms of intimate partner violence suffer greater damage to their health and are much more likely to attempt suicide, according to a study led by researchers at the University of Bristol’s Centre for Academic Primary Care published today [12 November] in the International Journal of Epidemiology.
Interactive virtual reality emerges as a new tool for drug design against COVID-1912 November 2020Bristol scientists have demonstrated a new virtual reality [VR] technique which should help in developing drugs against the SARS-CoV-2 virus – and enable researchers to share models and collaborate in new ways. The innovative tool, created by University of Bristol researchers, and published in the Journal of Chemical Information and Modeling, will help scientists around the world identify anti-viral drug leads more rapidly.
#8Investments to enable everyone, everywhere, to be physically active10 November 2020Researchers from the University of Bristol and NIHR ARC West have contributed to the International Society for Physical Activity and Health (ISPAH) ‘Eight Investments That Work for Physical Activity‘, released today [10 November].
Costs of informal end of life care are larger than formal care services10 November 2020An international study into the costs and outcomes of informal end of life care has found that in the UK, Ireland and the US, care provided by informal carers, meaning family and friends, accounted for more than half of total care costs in the last three months of life.
Analysis of Trump’s tweets reveals systematic diversion of the media10 November 2020President Donald Trump’s controversial use of social media is widely known and theories abound about its ulterior motives. New research published today in Nature Communications claims to provide the first evidence-based analysis demonstrating the US President’s Twitter account has been routinely deployed to divert attention away from a topic potentially harmful to his reputation, in turn suppressing negative related media coverage.
Bristol study completes COVID-19 antibody testing10 November 2020Children of the 90s, a health study based at the University of Bristol, has today published results from a study testing almost 5,000 participants for COVID-19 antibodies. 4.3% reported a positive result, of which a quarter were asymptomatic and did not report any symptoms in previous questionnaires.
New type of antivenom to reduce 100,000 fatalities each year from venomous snake bites being developed by Bristol scientists 5 November 2020A new approach of treating life-threatening snake bites responsible for around 100,000 deaths globally each year is being pioneered by an international research consortium led by University of Bristol scientists. The EU-funded ADDovenom study, involving teams in the UK, France, Belgium and Portugal, set out to create a new type of antivenom treatment to neutralise and eliminate venom toxins from the bloodstream with more efficacy, safety and affordability than what is available today.
Bristol COVID-19 experts to answer your questions4 November 2020COVID-19 has had an enormous impact on nearly every aspect of our everyday lives. In response, researchers from the University of Bristol are working together and with partners around the world to understand the virus, develop a vaccine and help bring an end to the pandemic.
Fossil poop shows fishy lunches from 200 million years ago2 November 2020A new study of coprolites, fossil poop, shows the detail of food webs in the ancient shallow seas around Bristol in south-west England. One hungry fish ate part of the head of another fish before snipping off the tail of a passing reptile.
Research to use artificial intelligence to identify sick livestock2 November 2020The welfare of livestock could be improved thanks to a new research project that will use novel artificial intelligence methods combined with behavioural analytics to provide rapid and reliable insights to animal health for farmers across the UK. The research and commercial feasibility program, co-funded by Innovate UK, the UK's innovation agency, will be led by the Quant Foundry (QF) in collaboration with the University of Bristol Vet School and Agri-EPI Centre.