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Fluid Dynamics in the human glomerulus: the formation of ultrafiltrate and possible counter-current enhancement of solute diffusion [or glomerular plumbing goes crazy!].
|
Dr Chris Neal, Dr Alberto Gambaruto
|
Bristol Renal |
|
Getting BADASS with the role of the renin angiotensin system in disease
|
Prof Patrick Kehoe, Prof Dek Woolfson, Dr Scott Miners |
Institute of Clinical Neuroscience |
|
Development of an isolated glomerular albumin permeability assay to high throughput for drug screening in human glomerular disease
|
Dr Rebecca Foster, Prof Simon Satchell, Prof Bruce Drinkwater |
Bristol Renal |
|
Endothelial glycocalyx as a novel therapeutic target in myocardial and renal ischemia reperfusion injuries
|
Prof Simon Satchell, Prof Saadeh Suleiman, Dr Raina Ramnath |
Bristol Renal |
|
Hyaluronic acid plays a key role in protecting against diabetic kidney disease
|
Dr Rebecca Foster, Prof Simon Satchell |
Bristol Renal |
|
Identification, characterisation and functional assessment of long non-coding RNA regulation of foam cell macrophage formation during atherosclerosis and aneurysm progression
|
Dr J Johnson, Dr K Di Gregoli |
Bristol CardioVascular |
|
Investigating intracellular signalling mechanisms in the hippocampus: implications in memory formation and disease
|
Prof James Uney, Dr Liang-Fong Wong
|
Bristol Neuroscience |
|
Investigating the timing and causes of vascular dysfunction in Alzheimer’s disease
|
Dr Scott Miners, Prof S Love
|
Institute of Clinical Neuroscience |
|
Mechanistic investigation of cardiac complications of COVID-19
|
Prof Paolo Madeddu, Dr Elisa Avolio |
Bristol CardioVascular |
| The role cardiac sympathetic stimulation in protecting the failing heart during cardioplegic arrest |
Prof Saadeh Suleiman, Dr Martin Lewis, Prof Massimo Caputo |
Bristol CardioVascular |
| A study of the natural history of joint hypermobility using a population-based birth cohort |
Dr Emma Clark, Prof Andy Judge, Prof Shea Palmer
|
Musculoskeletal |
|
Studies of brain renin angiotensin system changes in Parkinson’s disease to find new treatments
|
Prof Patrick Kehoe, Dr Scott Miners |
Institute of Clinical Neuroscience |
|
Investigating associations between the brain renin angiotensin system and Traumatic Brain Injury
|
Prof Patrick Kehoe, Dr Scott Miners, Dr Kanch Sharma |
Institute of Clinical Neuroscience |
|
Investigating the conflicting roles of the renin angiotensin system in Alzheimer’s disease
|
Prof Patrick Kehoe, Dr Scott Miners, |
Institute of Clinical Neuroscience |
|
Does the brain renin angiotensin system influence the occurrence of depression in Alzheimer’s disease?
|
Prof Patrick Kehoe, Dr Scott Miners, Dr Lindsey Sinclair |
Institute of Clinical Neuroscience |
|
Investigating the role of the renin angiotensin system in COVID19 patients
|
Prof Patrick Kehoe, Dr Scott Miners, Dr David Arnold |
Institute of Clinical Neuroscience |
|
Does ultrasound-mediated neuromodulation restore cellular function in Alzheimer’s disease?
|
Dr Daniel Whitcomb, Prof Bruce Drinkwater
|
Institute of Clinical Neuroscience |
|
Evaluation of novel therapies for human coronary artery bypass graft disease
|
Prof Sarah George, Dr Jason Johnson
|
Bristol CardioVascular |
|
The effect of age on arterial remodelling: relevance to atherosclerotic plaque progression and aneurysm formation
|
Prof Sarah George, Dr Jason Johnson
|
Bristol CardioVascular |
| Targeting acute inflammation to reduce coronary artery vein graft failure using bioengineering |
Prof Sarah George, Dr Jason Johnson |
Bristol CardioVascular |
| Investigating the role of the regulatory renin-angiotensin system in protecting against synaptic dysfunction in Alzheimer’s disease |
Dr Scott Miners, Dr Daniel Whitcomb |
Institute of Clinical Neuroscience |
| Understanding the mechanisms of human labour to improve management of preterm labour and induction of labour |
Dr Kate Birchenall, Dr Gavin Welsh |
Bristol Renal |
|
The role of GRP78 in the intrinsic actions of IGFBPs -2 and -3 in breast cancer
|
Dr Claire Perks, Dr Kalina Biernacka, Prof Jeff Holly |
IGFs and Metabolic Endocrinology Group |
| α-synuclein and microRNA function in human dopamine neurons |
Dr Liang-Fong Wong, Associate Prof Oscar Cordero-Llana |
Bristol Neuroscience |
| Characterising the stress response in human neurons derived from induced pluripotent stem cells |
Prof James Uney, Associate Prof Oscar Cordero-Llana |
Bristol Neuroscience |
|
Obesity, type 2 diabetes and the thrifty genotype hypothesis
|
Prof David Murphy, Prof Abdulaziz Alagaili, Kate Ellacott |
Bristol Neuroscience |
| Bio-fabricating constructs suitable for pulmonary valve replacement therapy in paediatric patients with congenital heart defect |
Dr M Ghorbel |
Bristol CardioVascular |
| Exploring 3D bio-printing technology for fabrication of cardiovascular tissue |
Dr M Ghorbel |
Bristol CardioVascular |
| A potential therapeutic role for insulin-like growth factor-I (IGF-I) in Alzheimer’s Disease |
Dr Claire Perks, Prof Patrick Kehoe, Dr Rachel Barker, Dr Shelley-Allen |
IGFs and Metabolic Endocrinology Group |
| Understanding and curing genetic kidney disease |
Dr Gavin Welsh, Prof Moin Saleem |
Bristol Renal |
| Identifying the causes and cellular effects of Focal segmental glomerulosclerosis (FSGS) |
Dr Gavin Welsh, Prof Moin Saleem |
Bristol Renal |
| Exploring the contribution of divergent neuroinflammation in Alzheimer’s disease |
Dr J Johnson, Prof Patrick Kehoe |
Bristol CardioVascular |
| Assessing neuroinflammation and vascular dementia in association with atherosclerosis and aneurysm risk |
Dr J Johnson, Prof Patrick Kehoe |
Bristol CardioVascular |
| Exploring the similarities between neointimal formation after vascular injury and tumour growth |
Dr Jason Johnson, Prof Sarah George |
Bristol CardioVascular |
