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Homelessness and unstable housing are associated with increased HIV and HCV risk among people who inject drugs

Press release issued: 26 March 2021

Homelessness and unstable housing are associated with a substantial increase in HIV and hepatitis C virus (HCV) acquisition risk among people who inject drugs, according to research led by the NIHR Health Protection Research Unit in Behavioural Science and Evaluation at the University of Bristol.

The study, published in The Lancet Public Health today [26 March] found that, among people who inject drugs, recent homelessness and unstable housing were associated with a 55 per cent and 65 per cent increase in HIV and HCV acquisition risk, respectively.

The study is the first systematic review and meta-analysis (a statistical method used to combine the results of multiple studies) to assess whether homelessness or unstable housing increases HIV or HCV risk among people who inject drugs. The researchers extracted and pooled data from 45 previous studies providing 70 estimates (26 for HIV and 44 for HCV) to work out a more robust measure of the risks.

Paper: Homelessness, unstable housing and risk of HIV and hepatitis C virus acquisition among people who inject drugs – a systematic review and meta-analysis by Chiedozie Arum et al. Published in The Lancet Public Health. [26 March 2021]

Read the full story on the University of Bristol press release

Further information

About the National Institute for Health Research
The National Institute for Health Research (NIHR) is the nation's largest funder of health and care research. The NIHR:

  • funds, supports and delivers high quality research that benefits the NHS, public health and social care
  • engages and involves patients, carers and the public in order to improve the reach, quality and impact of research
  • attracts, trains and supports the best researchers to tackle the complex health and care challenges of the future
  • invests in world-class infrastructure and a skilled delivery workforce to translate discoveries into improved treatments and services
  • partners with other public funders, charities and industry to maximise the value of research to patients and the economy.

The NIHR was established in 2006 to improve the health and wealth of the nation through research, and is funded by the Department of Health and Social Care. In addition to its national role, the NIHR supports applied health research for the direct and primary benefit of people in low- and middle-income countries, using UK aid from the UK government.

About the NIHR Health Protection Research Unit in Behavioural Science and Evaluation at University of Bristol

The NIHR HPRU in Behavioural Science and Evaluation at University of Bristol is one of 14 HPRUs across England, part of a £58.7 million investment by the NIHR to protect the health of the nation. The NIHR HPRU in Behavioural Science and Evaluation is a partnership between Public Health England and University of Bristol, in collaboration with MRC Biostatistics Research Unit at the University of Cambridge and University of the West of England. Each NIHR HPRU undertakes high quality research that is used by PHE to keep the public safe from current and emerging public health threats.

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