Small molecule characterisation
The 700MHz 1.7mm cryoprobe is 5-6 times more sensitive than a 600 MHz 5mm cryoprobe. It can acquire 1H 1D spectra in the nanogram range (for a small compounds) and acquire standard 2D 1H observe experiments such as 1H-13C HSQC spectra on a few micrograms. For less sensitive experiments (1,1-ADEQUATE/HCNMBC) milligrams are necessary.
In addition, the NMR suite supports:
- Computer-assisted structural elucidation.
- Highly sensitive, high resolution 1D and 2D data on < 60 nanomoles.
- High throughput, allowing structural elucidation to be achieved in minutes, especially when supplemented with mass spectrometry data and 1,1-ADEQUATE experiments.
- Bacterial and fungal genomics and natural product mining.