Collaborative COVID-19 lockdown effort delivers major boost for vaccine innovation in Bristol 7 October 2021Faster vaccine development could be a step closer thanks to £4 million investment to Imophoron Ltd, a Bristol University biotech start-up developing a novel, next generation rapid-response vaccine platform called ADDomer™. Imophoron will use the investment to bring ADDomer vaccines to clinical stage, initially targeting three viruses, RSV (respiratory syncytial virus), COVID-19, and mosquito-borne Chikungunya.
Bristol retains Strategic Partnership with the BBSRC and ranks fourth for bioscience research funding 30 September 2021The BBSRC, one of the UK’s largest UK bioscience funders, has announced Bristol will retain its Strategic Partnership (SP) status. The decision was announced this month following BBSRC’s SP member triannual review. Bristol is one of only ten top-funded university partners with this status – which it has retained since 2012 recognising the University’s long-term record for excellence in biosciences research.
How vitamins, steroids and potential antivirals might affect SARS-CoV-228 January 2021Evidence is emerging that vitamin D – and possibly vitamins K and A – might help combat COVID-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown how they – and other antiviral drugs – might work. The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so might reduce SARS-CoV-2 infectivity. In contrast, cholesterol may increase infectivity, which could explain why having high cholesterol is considered a risk factor for serious disease.
Discovery of a druggable pocket in the SARS-CoV-2 Spike protein could stop virus in its tracks21 September 2020A druggable pocket in the SARS-CoV-2 Spike protein that could be used to stop the virus from infecting human cells has been discovered by an international team of scientists led by the University of Bristol. The researchers say their findings, published today [21 September] in the journal Science, are a potential 'game changer' in defeating the current pandemic and add that small molecule anti-viral drugs developed to target the pocket they discovered could help eliminate COVID-19.
German Ambassador visits the University 7 September 2020Andreas Michaelis, German Ambassador to the Court of St James's, visited Bristol on Wednesday 2 September accompanied by his wife Frau Heike Michaelis, German Consul General Hans-Guenther Loeffler, and the new Honorary German Consul for Bristol Kai von Pahlen.
Technology takes a step forwards in genetic research11 February 2020New research brings combined computational and laboratory genome engineering a step closer following the design of smaller and smaller genomes, to advance genetic manipulation, using supercomputers by researchers at the University of Bristol.
Catalytic protocells get zingy8 January 2020Artificial cells capable of oxygen gas production and chemical signalling have been prepared using a combination of synthetic and biological catalysts through an international collaboration between the University of Bristol and the University of Padua in Italy.
UK scientists bring innovative vaccine technology to Vietnam27 November 2019World-leading vaccine scientists from the University of Bristol are working with one of Vietnam's major vaccine manufacturers, Vabiotech, to share cutting-edge knowledge that could help prevent future global outbreaks of avian flu and rabies.
Health pioneers celebrated at awards for life-changing chemistry innovations31 October 2019University of Bristol spin-out, Rosa Biotech, was named as one of the most exciting health chemistry innovators in Europe after winning a Royal Society of Chemistry (RSC) Emerging Technologies 2019 award for its biosensing platform that mimics the mammalian olfactory (smelling) system. Rosa was one of two innovations to win the award and a share of £80,000 prize.
University of Bristol spin-out raises £760,000 to commercialise biosensing technology31 October 2019Rosa Biotech, a new University of Bristol spin-out which developed a sensing platform capable of detecting the faint chemical signature given off by chronic diseases has raised £760,000 to commercialise its ground-breaking innovation. The artificial Intelligence (AI)-driven biosensing technology, which mimics mammals’ sense of smell, has significant potential to transform the medical diagnostics and pharmaceuticals industries.
Powerful new synthetic vaccines to combat epidemics25 September 2019A new type of vaccine that can be stored at warmer temperatures, removing the need for refrigeration, has been developed for mosquito-borne virus Chikungunya in a major advance in vaccine technology. The findings, published in Science Advances today [Wednesday 25 September], reveal exceptionally promising results for the Chikungunya vaccine candidate, which has been engineered using a synthetic protein scaffold that could revolutionise the way vaccines are designed, produced and stored.
Scientists hijack bacteria's homing ability3 July 2019In a world first, scientists have found a new way to direct stem cells to heart tissue. The findings, led by researchers at the University of Bristol and published in Chemical Science, could radically improve the treatment for cardiovascular disease, which causes more than a quarter of all deaths in the UK (1).