Protocol and information
Best Emollients in Eczema (BEE): Pragmatic, primary care, multi-centre, individually randomised superiority trial of four emollients in children with eczema, with internal pilot, nested economic evaluation and qualitative study
Study protocol
Version 7.0 of the study protocol (19 November 2019) which describes in detail the back ground to and conduct of the study.
BEE Protocol version 7.0 (PDF, 930kB)
Statistical Analysis Plan
Version 1.2 of the SAP (16 October 2020) which details the rules proposed and the presentation that will be followed, as closely as possible, when analysing and reporting the main results from the study.
BEE SAP v1.2 final 2020 (PDF, 747kB)
Study information leaflets
For participants:
The study flyer summarises the study on a single page
BEE Invite Flyer (PDF, 255kB)
Patient Information Sheet gives more detailed information for parents/carers
BEE Participant Information Sheet (PDF, 352kB)
Child Information Sheet describes the study in a more child-friendly way.
BEE Child Information Sheet (PDF, 400kB)
Qualitative study participant information sheet
BEE Qualitative Study Participant Information Sheet (PDF, 281kB)
Extra Information for parents about how your data is handled in light of new EU General Data Protection Regulations (GDPR).
GDPR Extra Information for Parents (PDF, 110kB)
For GP surgeries:
The research information sheet summarises the background and aims of the study, and what is involved for participating practices and their parents.
Feasibility study (COMET: Choice of Moisturiser for Eczema Treatment)
The BEE study will build on previous trial findings from the COMET study, which investigated whether it was feasible to recruit and randomise young children with eczema to one moisturiser, follow them up and collect study data, whilst keeping observers blind to their treatment allocation.
More information and the results of this study can be found here