2015 Publications
Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. S., Wannamethee, S. G., Lahti, J., Raikkonen, K., Palotie, A., Wong, A., Dalgård, C., Ford, I., Ben-Shlomo, Y., Christiansen, L., Kyvik, K. O., Kuh, D. J. L., Eriksson, J. G., Whincup, P. H., Mbarek, H., De Geus, E. J. C., Vink, J. M., Boomsma, D. I., Smith, G. D., Lawlor, D. A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J. W., Power, C., Hypponen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimaki, M. J., Smith, B. H., Hayward, C., Sorensen, T., Thuesen, B. H., Sattar, N., Morris, R. W., Romundstad, P. R., Munafò, M. R., Jarvelin, M. R. & Husemoen, L. L. N., 1 Dec 2015, In : Circulation: Cardiovascular Genetics. 8, 6, p.832-841
Cardiovascular and neuropsychiatric risks of varenicline: too good to be true? Davies, N., Taylor, G., Taylor, A., Martin, R., Munafo, M. & Thomas, K., Dec 2015, Lancet Respiratory Medicine, 3, 12, p.e39-e40
What are the effects of varenicline compared with nicotine replacement therapy on long-term smoking cessation and clinically important outcomes? Protocol for a prospective cohort study Davies, N. M., Taylor, G. M. J., Taylor, A. E., Thomas, K. H., Windmeijer, F., Martin, R. M. & Munafo, M. R., 5 Nov 2015, In : BMJ Open. 5, 11, , e009665
Smoking and diabetes risk: building a causal case with clinical implications Sattar, N., Taylor, A. E., Sorensen, T., Morris, R. & Munafò, M. R., 17 Sep 2015, In : Lancet Diabetes and Endocrinology.
Exploring causal associations of alcohol with cardiovascular and metabolic risk factors in a Chinese population using Mendelian randomization analysis Taylor, A. E., Lu, F., Carslake, D. J., Hu, Z., Qian, Y., Liu, S., Chen, J., Chen, H. & Davey Smith, G., 14 Sep 2015, In : Scientific Reports. 5, , 14005
Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G., Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sorensen, T., Munafò, M. R. & Sattar, N., 11 Aug 2015, In : BMJ Open. 5, 8, , e008808
Smoking and diabetes: Strengthening causal inference Taylor, A. E., Davies, N. M. & Munafò, M. R., 1 Jun 2015, In : Lancet Diabetes and Endocrinology. 3, 6, p.395-396
Does smoking reduction worsen mental health? A comparison of two observational approaches Taylor, G. M. J., Taylor, A. E., Munafo, M. R., McNeill, A. & Aveyard, P., 15 May 2015, In : BMJ Open. 5, 5, , e007812
Using molecular genetic information to infer causality in observational data: Mendelian randomisation Taylor, A. E., Ware, J. J., Gage, S. H., Smith, G. D. & Munafò, M. R., 1 Apr 2015, In : Current Opinion in Behavioral Sciences. 2, p.39-45
Associations between diet, physical activity and body fat distribution: a cross sectional study in an Indian population Bowen, L., Taylor, A. E., Sullivan, R., Ebrahim, S., Kinra, S., Krishna, K. V. R., Kulkarni, B., Ben-Shlomo, Y., Ekelund, U., Wells, J. C. & Kuper, H., 2015, In : BMC Public Health. 15, p.281
Is the Association between Vitamin D and Cardiovascular Disease Risk Confounded by Obesity? Evidence from the Andhra Pradesh Children and Parents Study (APCAPS) Baker, C. P., Kulkarni, B., Radhakrishna, K. V., Charyulu, M. S., Gregson, J., Matsuzaki, M., Taylor, A. E., Prabhakaran, D., Mamidi, R. S., Wells, J., Wilkinson, I., McEniery, C., Yasmin, N. V., Davey Smith, G., Ben-Shlomo, Y., Kuper, H. & Kinra, S., 2015, In : PLoS ONE. 10, 6, p.e0129468
Digit ratio and autism spectrum disorders in the Avon Longitudinal Study of Parents and Children: a birth cohort study Guyatt, A. L., Heron, J. E., Knight, B. L. C., Golding, J. & Rai, D., Aug 2015, In : BMJ Open. 5, 8, , e007433
Copy number variations and cognitive phenotypes in unselected populations Männik, K., Mägi, R., Macé, A., Cole, B., Guyatt, A. L., Shihab, H. A., Maillard, A. M., Alavere, H., Kolk, A., Reigo, A., Mihailov, E., Leitsalu, L., Ferreira, A-M., Nõukas, M., Teumer, A., Salvi, E., Cusi, D., McGue, M., Iacono, W. G., Gaunt, T. R., Beckmann, J. S., Jacquemont, S., Kutalik, Z., Pankratz, N., Timpson, N., Metspalu, A. & Reymond, A., 26 May 2015, In : JAMA - Journal of the American Medical Association. 313, 20, p.2044-54
Association of socio-economic position and suicide/attempted suicide in low and middle income countries in South and South-East Asia - a systematic review Knipe, D. W., Carroll, R., Thomas, K. H., Pease, A., Gunnell, D. & Metcalfe, C., 15 Oct 2015, In : BMC Public Health. 15, 1055, p.1-18
WHO suicide statistics - a cautionary tale Knipe, D., Metcalfe, C. & Gunnell, D., 17 Mar 2015, In : Ceylon Medical Journal. 60, 1, p.35
Risk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysis Thomas, K. H., Martin, R. M., Knipe, D. W., Higgins, J. P. T. & Gunnell, D., 12 Mar 2015, In : BMJ. 350, , h1109
Omega-3 fatty acids for depression in adults Appleton, K. M., Sallis, H. M., Perry, R., Ness, A. R. & Churchill, R., 5 Nov 2015, In : Cochrane Database of Systematic Reviews. 11,
Emotion generation and regulation in anorexia nervosa: A systematic review and meta-analysis of self-report data Oldershaw, A., Lavender, T., Sallis, H., Stahl, D. & Schmidt, U., Jul 2015, In : Clin Psychol Forum. 39, p.83-95
Reasons for cannabis use in first-episode psychosis: Does strength of endorsement change over 12 months? Kolliakou, A., Castle, D., Sallis, H., Joseph, C., O'Connor, J., Wiffen, B., Gayer-Anderson, C., McQueen, G., Taylor, H., Bonaccorso, S., Gaughran, F., Smith, S., Greenwood, K., Murray, R. M., Di Forti, M., Atakan, Z. & Ismail, K., 1 Jan 2015, In : European Psychiatry. 30, 1, p.152-159
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation María Soler Artigas, Louise V Wain, Suzanne Miller, Abdul Kader Kheirallah, Jennifer E Huffman, Ioanna Ntalla, Nick Shrine, Holly Trochet, Wendy L McArdle, Alexessander Couto Alves, Jennie Hui, Jing Hua Zhao, Peter K Joshi, Alexander Teumer, Eva Albrecht, Medea Imboden, Rajesh Rawal, Lorna M Lopez, Jonathan Marten, Stefan Enroth, Ida Surakka, Ozren Polasek, Leo-Pekka Lyytikäinen, Raquel Granell, Pirro G Hysi, Claudia Flexeder, Anubha Mahajan, John Beilby, Yohan Bossé, Corry-Anke Brandsma, Harry Campbell, Christian Gieger, Sven Gläser, Juan R González, Harald Grallert, Chris J Hammond, Sarah E Harris, Anna-Liisa Hartikainen, Markku Heliövaara, John Henderson, Lynne Hocking, Momoko Horikoshi, Nina Hutri-Kähönen, Erik Ingelsson, Åsa Johansson, John P Kemp, Ivana Kolcic, Ashish Kumar, Lars Lind, Erik Melén, Arthur W Musk, Pau Navarro, David C Nickle, Sandosh Padmanabhan, Olli T Raitakari, Janina S Ried, Samuli Ripatti, Holger Schulz, Robert A Scott, Don D Sin, John M Starr, UK BiLEVE, Panos Deloukas, Anna L Hansell, Richard Hubbard, Victoria E Jackson, Jonathan Marchini, Ian Pavord, Neil C Thomson, Eleftheria Zeggini, Ana Viñuela, Henry Völzke, Sarah H Wild, Alan F Wright, Tatijana Zemunik, Deborah L Jarvis, Tim D Spector, David M Evans, Terho Lehtimäki, Veronique Vitart, Mika Kähönen, Ulf Gyllensten, Igor Rudan, Ian J Deary, Stefan Karrasch, Nicole M Probst-Hensch, Joachim Heinrich, Beate Stubbe, James F Wilson, Nicholas J Wareham, Alan L James, Andrew P Morris, Marjo-Riitta Jarvelin, Caroline Hayward, Ian Sayers, David P Strachan, Ian P Hall, Martin D Tobin
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis Lavinia Paternoster, Marie Standl, Johannes Waage, Hansjörg Baurecht, Melanie Hotze, David P Strachan, John A Curtin, Klaus Bønnelykke, Chao Tian, Atsushi Takahashi, Jorge Esparza-Gordillo, Alexessander Couto Alves, Jacob P Thyssen, Herman T den Dekker, Manuel A Ferreira, Elisabeth Altmaier, Patrick MA Sleiman, Feng Li Xiao, Juan R Gonzalez, Ingo Marenholz, Birgit Kalb, Maria Pino-Yanes, Cheng-Jian Xu, Lisbeth Carstensen, Maria M Groen-Blokhuis, Cristina Venturini, Craig E Pennell, Sheila J Barton, Albert M Levin, Ivan Curjuric, Mariona Bustamante, Eskil Kreiner-Møller, Gabrielle A Lockett, Jonas Bacelis, Supinda Bunyavanich, Rachel A Myers, Anja Matanovic, Ashish Kumar, Joyce Y Tung, Tomomitsu Hirota, Michiaki Kubo, Wendy L McArdle, A John Henderson, John P Kemp, Jie Zheng, George Davey Smith, Franz Rüschendorf, Anja Bauerfeind, Min Ae Lee-Kirsch, Andreas Arnold, Georg Homuth, Carsten O Schmidt, Elisabeth Mangold, Sven Cichon, Thomas Keil, Elke Rodríguez, Annette Peters, Andre Franke, Wolfgang Lieb, Natalija Novak, Regina Fölster-Holst, Momoko Horikoshi, Juha Pekkanen, Sylvain Sebert, Lise L Husemoen, Niels Grarup, Johan C De Jongste, Fernando Rivadeneira, Albert Hofman, Vincent WV Jaddoe, Suzanne GMA Pasmans, Niels J Elbert, André G Uitterlinden, Guy B Marks, Philip J Thompson, Melanie C Matheson, Colin F Robertson, Janina S Ried, Jin Li, Xian Bo Zuo, Xiao Dong Zheng, Xian Yong Yin, Liang Dan Sun, Maeve A McAleer, Grainne M O'Regan, Caoimhe MR Fahy, Linda E Campbell, Milan Macek, Michael Kurek, Donglei Hu, Celeste Eng, Dirkje S Postma, Bjarke Feenstra, Frank Geller, Jouke Jan Hottenga, Christel M Middeldorp, Pirro Hysi, Veronique Bataille, Tim Spector, Carla MT Tiesler, Elisabeth Thiering, Badri Pahukasahasram, James J Yang, Medea Imboden, Scott Huntsman, Natàlia Vilor-Tejedor, Caroline L Relton, Ronny Myhre, Wenche Nystad, Adnan Custovic, Scott T Weiss, Deborah A Meyers, Cilla Söderhäll, Erik Melén, Carole Ober, Benjamin A Raby, Angela Simpson, Bo Jacobsson, John W Holloway, Hans Bisgaard, Jordi Sunyer, Nicole M Probst-Hensch, L Keoki Williams, Keith M Godfrey, Carol A Wang, Dorret I Boomsma, Mads Melbye, Gerard H Koppelman, Deborah Jarvis, WH Irwin McLean, Alan D Irvine, Xue Jun Zhang, Hakon Hakonarson, Christian Gieger, Esteban G Burchard, Nicholas G Martin, Liesbeth Duijts, Allan Linneberg, Marjo-Riitta Jarvelin, Markus M Nöthen, Susanne Lau, Norbert Hübner, Young-Ae Lee, Mayumi Tamari, David A Hinds, Daniel Glass, Sara J Brown, Joachim Heinrich, David M Evans, Stephan Weidinger
The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium Neil M Davies, Tom R Gaunt, Sarah J Lewis, Jeff Holly, Jenny L Donovan, Freddie C Hamdy, John P Kemp, Rosalind Eeles, Doug Easton, Zsofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G Giles, Fredrik Wiklund, Henrik Gronberg, Christopher A Haiman, Johanna Schleutker, Børge G Nordestgaard, Ruth C Travis, David Neal, Nora Pashayan, Kay-Tee Khaw, Janet L Stanford, William J Blot, Stephen Thibodeau, Christiane Maier, Adam S Kibel, Cezary Cybulski, Lisa Cannon-Albright, Hermann Brenner, Jong Park, Radka Kaneva, Jyotsna Batra, Manuel R Teixeira, Hardev Pandha, Mark Lathrop, George Davey Smith, Richard M Martin, PRACTICAL consortium
Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy Rebecca Gilbert, Richard M Martin, David M Evans, Kate Tilling, George Davey Smith, John P Kemp, J Athene Lane, Freddie C Hamdy, David E Neal, Jenny L Donovan, Chris Metcalfe
Whole‐genome sequencing identifies EN1as a determinant of bone density and fracture Hou‐Feng Zheng, Vincenzo Forgetta, Yi‐Hsiang Hsu, Karol Estrada, Alberto Rosello‐Diez, Paul J Leo, Chitra L Dahia, Kyung Hyun Park‐Min, Jonathan H Tobias, Charles Kooperberg, Aaron Kleinman, Unnur Styrkarsdottir, Ching‐Ti Liu, Charlotta Uggla, Daniel S Evans, Carrie M Nielson, Klaudia Walter, Ulrika Pettersson‐Kymmer, Shane McCarthy, Joel Eriksson, Tony Kwan, Mila Jhamai, Katerina Trajanoska, Yasin Memari, Josine Min, Jie Huang, Petr Danecek, Beth Wilmot, Rui Li, Wen‐Chi Chou, Lauren E Mokry, Alireza Moayyeri, Melina Claussnitzer, Chia‐Ho Cheng, Warren Cheung, Carolina Medina‐Gómez, Bing Ge, Shu‐Huang Chen, Kwangbom Choi, Ling Oei, James Fraser, Robert Kraaij, Matthew A Hibbs, Celia L Gregson, Denis Paquette, Albert Hofman, Carl Wibom, Gregory J Tranah, Mhairi Marshall, Brooke B Gardiner, Katie Cremin, Paul Auer, Li Hsu, Sue Ring, Joyce Y Tung, Gudmar Thorleifsson, Anke W Enneman, Natasja M Van Schoor, Lisette CPGM De Groot, Nathalie Van Der Velde, Beatrice Melin, John P Kemp, Claus Christiansen, Adrian Sayers, Yanhua Zhou, Sophie Calderari, Jeroen Van Rooij, Chris Carlson, Ulrike Peters, Soizik Berlivet, Josée Dostie, Andre G Uitterlinden, Stephen R Williams, Charles Farber, Daniel Grinberg, Andrea Z LaCroix, Jeff Haessler, Daniel I Chasman, Franco Giulianini, Lynda M Rose, Paul M Ridker, John A Eisman, Tuan V Nguyen, Jacqueline R Center, Xavier Nogues, Natalia Garcia‐Giralt, Lenore L Launer, Vilmunder Gudnason, Dan Mellström, Liesbeth Vandenput, Najaf Amin, Cornelia M Van Duijn, Magnus K Karlsson, Östen Ljunggren, Olle Svensson, Göran Hallmans, François Rousseau, Sylvie Giroux, Johanne Bussière, Pascal P Arp, Fjorda Koromani, Richard L Prince, Joshua R Lewis, Bente L Langdahl, A Pernille Hermann, Jens‐Erik B Jensen, Stephen Kaptoge, Kay‐Tee Khaw, Jonathan Reeve, Melissa M Formosa, Angela Xuereb‐Anastasi, Kristina Åkesson, Fiona E McGuigan, Gaurav Garg, Jose M Olmos, Maria T Zarrabeitia, Jose A Riancho, Stuart H Ralston, Nerea Alonso, Xi Jiang, David Goltzman, Tomi Pastinen, Elin Grundberg, Dominique Gauguier, Eric S Orwoll, David Karasik, George Davey‐Smith, Albert V Smith, Kristin Siggeirsdottir, Tamara B Harris, M Carola Zillikens, Joyce BJ Van Meurs, Unnur Thorsteinsdottir, Matthew T Maurano, Nicholas J Timpson, Nicole Soranzo, Richard Durbin, Scott G Wilson, Evangelia E Ntzani, Matthew A Brown, Kari Stefansson, David A Hinds, Tim Spector, L Adrienne Cupples, Claes Ohlsson, Celia MT Greenwood, Rebecca D Jackson, David W Rowe, Cynthia A Loomis, David M Evans
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel Jie Huang, Bryan Howie, Shane McCarthy, Yasin Memari, Klaudia Walter, Josine L Min, Petr Danecek, Giovanni Malerba, Elisabetta Trabetti, Hou-Feng Zheng, Saeed Al Turki, Antoinette Amuzu, Carl A Anderson, Richard Anney, Dinu Antony, María Soler Artigas, Muhammad Ayub, Senduran Bala, Jeffrey C Barrett, Inês Barroso, Phil Beales, Marianne Benn, Jamie Bentham, Shoumo Bhattacharya, Ewan Birney, Douglas Blackwood, Martin Bobrow, Elena Bochukova, Patrick F Bolton, Rebecca Bounds, Chris Boustred, Gerome Breen, Mattia Calissano, Keren Carss, Juan Pablo Casas, John C Chambers, Ruth Charlton, Krishna Chatterjee, Lu Chen, Antonio Ciampi, Sebahattin Cirak, Peter Clapham, Gail Clement, Guy Coates, Massimiliano Cocca, David A Collier, Catherine Cosgrove, Tony Cox, Nick Craddock, Lucy Crooks, Sarah Curran, David Curtis, Allan Daly, Ian NM Day, Aaron Day-Williams, George Dedoussis, Thomas Down, Yuanping Du, Cornelia M Van Duijn, Ian Dunham, Sarah Edkins, Rosemary Ekong, Peter Ellis, David M Evans, I Sadaf Farooqi, David R Fitzpatrick, Paul Flicek, James Floyd, A Reghan Foley, Christopher S Franklin, Marta Futema, Louise Gallagher, Paolo Gasparini, Tom R Gaunt, Matthias Geihs, Daniel Geschwind, Celia Greenwood, Heather Griffin, Detelina Grozeva, Xiaosen Guo, Xueqin Guo, Hugh Gurling, Deborah Hart, Audrey E Hendricks, Peter Holmans, Liren Huang, Tim Hubbard, Steve E Humphries, Matthew E Hurles, Pirro Hysi, Valentina Iotchkova, Aaron Isaacs, David K Jackson, Yalda Jamshidi, Jon Johnson, Chris Joyce, Konrad J Karczewski, Jane Kaye, Thomas Keane, John P Kemp, Karen Kennedy, Alastair Kent, Julia Keogh, Farrah Khawaja, Marcus E Kleber, Margriet Van Kogelenberg, Anja Kolb-Kokocinski, Jaspal S Kooner, Genevieve Lachance, Claudia Langenberg, Cordelia Langford, Daniel Lawson, Irene Lee, Elisabeth M Van Leeuwen, Monkol Lek, Rui Li, Yingrui Li, Jieqin Liang, Hong Lin, Ryan Liu, Jouko Lönnqvist, Luis R Lopes, Margarida Lopes, Jian'an Luan, Daniel G MacArthur, Massimo Mangino, Gaëlle Marenne, Winfried März, John Maslen, Angela Matchan, Iain Mathieson, Peter McGuffin, Andrew M McIntosh, Andrew G McKechanie, Andrew McQuillin, Sarah Metrustry, Nicola Migone, Hannah M Mitchison, Alireza Moayyeri, James Morris, Richard Morris, Dawn Muddyman, Francesco Muntoni, Børge G Nordestgaard, Kate Northstone, Michael C O'donovan, Stephen O'rahilly, Alexandros Onoufriadis, Karim Oualkacha, Michael J Owen
Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium Stephanie M van Den Berg, Marleen HM de Moor, Karin JH Verweij, Robert F Krueger, Michelle Luciano, Alejandro Arias Vasquez, Lindsay K Matteson, Jaime Derringer, Tõnu Esko, Najaf Amin, Scott D Gordon, Narelle K Hansell, Amy B Hart, Ilkka Seppälä, Jennifer E Huffman, Bettina Konte, Jari Lahti, Minyoung Lee, Mike Miller, Teresa Nutile, Toshiko Tanaka, Alexander Teumer, Alexander Viktorin, Juho Wedenoja, Abdel Abdellaoui, Goncalo R Abecasis, Daniel E Adkins, Arpana Agrawal, Jüri Allik, Katja Appel, Timothy B Bigdeli, Fabio Busonero, Harry Campbell, Paul T Costa, George Davey Smith, Gail Davies, Harriet de Wit, Jun Ding, Barbara E Engelhardt, Johan G Eriksson, Iryna O Fedko, Luigi Ferrucci, Barbara Franke, Ina Giegling, Richard Grucza, Annette M Hartmann, Andrew C Heath, Kati Heinonen, Anjali K Henders, Georg Homuth, Jouke-Jan Hottenga, William G Iacono, Joost Janzing, Markus Jokela, Robert Karlsson, John P Kemp, Matthew G Kirkpatrick, Antti Latvala, Terho Lehtimäki, David C Liewald, Pamela AF Madden, Chiara Magri, Patrik KE Magnusson, Jonathan Marten, Andrea Maschio, Hamdi Mbarek, Sarah E Medland, Evelin Mihailov, Yuri Milaneschi, Grant W Montgomery, Matthias Nauck, Michel G Nivard, Klaasjan G Ouwens, Aarno Palotie, Erik Pettersson, Ozren Polasek, Yong Qian, Laura Pulkki-Råback, Olli T Raitakari, Anu Realo, Richard J Rose, Daniela Ruggiero, Carsten O Schmidt, Wendy S Slutske, Rossella Sorice, John M Starr, Beate St Pourcain, Angelina R Sutin, Nicholas J Timpson, Holly Trochet, Sita Vermeulen, Eero Vuoksimaa, Elisabeth Widen, Jasper Wouda, Margaret J Wright, Lina Zgaga, David Porteous, Alessandra Minelli, Abraham A Palmer, Dan Rujescu, Marina Ciullo, Caroline Hayward, Igor Rudan, Andres Metspalu, Jaakko Kaprio, Ian J Deary, Katri Räikkönen, James F Wilson, Liisa Keltikangas-Järvinen, Laura J Bierut, John M Hettema, Hans J Grabe, Brenda WJH Penninx, Cornelia M van Duijn, David M Evans, David Schlessinger, Nancy L Pedersen, Antonio Terracciano, Matt McGue, Nicholas G Martin, Dorret I Boomsma, Generation Scotland
Genetic variants in adult bone mineral density and fracture risk genes are associated with the rate of bone mineral density acquisition in adolescence Nicole M Warrington, John P Kemp, Kate Tilling, Jonathan H Tobias, David M Evans
Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder Marleen HM de Moor, Stéphanie M van den Berg, Karin JH Verweij, Robert F Krueger, Michelle Luciano, Alejandro Arias Vasquez, Lindsay K Matteson, Jaime Derringer, Tõnu Esko, Najaf Amin, Scott D Gordon, Narelle K Hansell, Amy B Hart, Ilkka Seppälä, Jennifer E Huffman, Bettina Konte, Jari Lahti, Minyoung Lee, Mike Miller, Teresa Nutile, Toshiko Tanaka, Alexander Teumer, Alexander Viktorin, Juho Wedenoja, Goncalo R Abecasis, Daniel E Adkins, Arpana Agrawal, Jüri Allik, Katja Appel, Timothy B Bigdeli, Fabio Busonero, Harry Campbell, Paul T Costa, George Davey Smith, Gail Davies, Harriet de Wit, Jun Ding, Barbara E Engelhardt, Johan G Eriksson, Iryna O Fedko, Luigi Ferrucci, Barbara Franke, Ina Giegling, Richard Grucza, Annette M Hartmann, Andrew C Heath, Kati Heinonen, Anjali K Henders, Georg Homuth, Jouke-Jan Hottenga, William G Iacono, Joost Janzing, Markus Jokela, Robert Karlsson, John P Kemp, Matthew G Kirkpatrick, Antti Latvala, Terho Lehtimäki, David C Liewald, Pamela AF Madden, Chiara Magri, Patrik KE Magnusson, Jonathan Marten, Andrea Maschio, Sarah E Medland, Evelin Mihailov, Yuri Milaneschi, Grant W Montgomery, Matthias Nauck, Klaasjan G Ouwens, Aarno Palotie, Erik Pettersson, Ozren Polasek, Yong Qian, Laura Pulkki-Råback, Olli T Raitakari, Anu Realo, Richard J Rose, Daniela Ruggiero, Carsten O Schmidt, Wendy S Slutske, Rossella Sorice, John M Starr, Beate St Pourcain, Angelina R Sutin, Nicholas J Timpson, Holly Trochet, Sita Vermeulen, Eero Vuoksimaa, Elisabeth Widen, Jasper Wouda, Margaret J Wright, Lina Zgaga, David Porteous, Alessandra Minelli, Abraham A Palmer, Dan Rujescu, Marina Ciullo, Caroline Hayward, Igor Rudan, Andres Metspalu, Jaakko Kaprio, Ian J Deary, Katri Räikkönen, James F Wilson, Liisa Keltikangas-Järvinen, Laura J Bierut, John M Hettema, Hans J Grabe, Cornelia M van Duijn, David M Evans, David Schlessinger, Nancy L Pedersen, Antonio Terracciano, Matt McGue, Brenda WJH Penninx, Nicholas G Martin, Dorret I Boomsma
Heritability and genome-wide analyses of problematic peer relationships during childhood and adolescence Beate St Pourcain, CMA Haworth, Oliver SP Davis, Kai Wang, Nicholas J Timpson, David M Evans, John P Kemp, Angelica Ronald, Tom Price, Emma Meaburn, Susan M Ring, Jean Golding, Hakon Hakonarson, Robert Plomin, George Davey Smith
A genome-wide association study of body mass index across early life and childhood Nicole M Warrington, Laura D Howe, Lavinia Paternoster, Marika Kaakinen, Sauli Herrala, Ville Huikari, Yan Yan Wu, John P Kemp, Nicholas J Timpson, Beate St Pourcain, George Davey Smith, Kate Tilling, Marjo-Riitta Jarvelin, Craig E Pennell, David M Evans, Debbie A Lawlor, Laurent Briollais, Lyle J Palmer
Genome-wide association study of blood lead shows multiple associations near ALAD Nicole M Warrington, Gu Zhu, Veronica Dy, Andrew C Heath, Pamela AF Madden, Gibran Hemani, John P Kemp, George Mcmahon, Beate St Pourcain, Nicholas J Timpson, Caroline M Taylor, Jean Golding, Debbie A Lawlor, Colin Steer, Grant W Montgomery, Nicholas G Martin, George Davey Smith, David M Evans, John B Whitfield
Whole-genome sequence-based analysis of thyroid function Peter N Taylor, Eleonora Porcu, Shelby Chew, Purdey J Campbell, Michela Traglia, Suzanne J Brown, Benjamin H Mullin, Hashem A Shihab, Josine Min, Klaudia Walter, Yasin Memari, Jie Huang, Michael R Barnes, John P Beilby, Pimphen Charoen, Petr Danecek, Frank Dudbridge, Vincenzo Forgetta, Celia Greenwood, Elin Grundberg, Andrew D Johnson, Jennie Hui, Ee M Lim, Shane McCarthy, Dawn Muddyman, Vijay Panicker, John RB Perry, Jordana T Bell, Wei Yuan, Caroline Relton, Tom Gaunt, David Schlessinger, Goncalo Abecasis, Francesco Cucca, Gabriela L Surdulescu, Wolfram Woltersdorf, Eleftheria Zeggini, Hou-Feng Zheng, Daniela Toniolo, Colin M Dayan, Silvia Naitza, John P Walsh, Tim Spector, George Davey Smith, Richard Durbin, J Brent Richards, Serena Sanna, Nicole Soranzo, Nicholas J Timpson, Scott G Wilson, Saeed Al Turki, Carl Anderson, Richard Anney, Dinu Antony, Maria Soler Artigas, Muhammad Ayub, Senduran Balasubramaniam, Jeffrey C Barrett, Inês Barroso, Phil Beales, Jamie Bentham, Shoumo Bhattacharya, Ewan Birney, Douglas Blackwood, Martin Bobrow, Elena Bochukova, Patrick Bolton, Rebecca Bounds, Chris Boustred, Gerome Breen, Mattia Calissano, Keren Carss, Krishna Chatterjee, Lu Chen, Antonio Ciampi, Sebhattin Cirak, Peter Clapham, Gail Clement, Guy Coates, David Collier, Catherine Cosgrove, Tony Cox, Nick Craddock, Lucy Crooks, Sarah Curran, David Curtis, Allan Daly, Aaron Day-Williams, Ian NM Day, Thomas Down, Yuanping Du, Ian Dunham, Sarah Edkins, Peter Ellis, David Evans, Sadaf Faroogi, Ghazaleh Fatemifar, David R Fitzpatrick, Paul Flicek, James Flyod, A Reghan Foley, Christopher S Franklin, Marta Futema, Louise Gallagher, Matthias Geihs, Daniel Geschwind, Heather Griffin, Detelina Grozeva, Xueqin Guo, Xiaosen Guo, Hugh Gurling, Deborah Hart, Audrey Hendricks, Peter Holmans, Bryan Howie, Liren Huang, Tim Hubbard, Steve E Humphries, Matthew E Hurles, Pirro Hysi, David K Jackson, Yalda Jamshidi, Tian Jing, Chris Joyce, Jane Kaye, Thomas Keane, Julia Keogh, John Kemp, Karen Kennedy, Anja Kolb-Kokocinski, Genevieve Lachance, Cordelia Langford, Daniel Lawson, Irene Lee, Monkol Lek, Jieqin Liang, Hong Lin, Rui Li, Yingrui Li, Ryan Liu, Jouko Lönnqvist, Margarida Lopes, Valentina Iotchkova, Daniel MacArthur, Jonathan Marchini, John Maslen, Mangino Massimo, Iain Mathieson, Gaëlle Marenne, Peter McGuffin
Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1, 25-dihydroxyvitamin-D, and prostate cancer: a nested case–control study Rebecca Gilbert, Carolina Bonilla, Chris Metcalfe, Sarah Lewis, David M Evans, William D Fraser, John P Kemp, Jenny L Donovan, Freddie C Hamdy, David E Neal, J Athene Lane, George Davey Smith, Mark Lathrop, Richard M Martin
Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium Qing Li, Robert Wojciechowski, Claire L Simpson, Pirro G Hysi, Virginie JM Verhoeven, Mohammad Kamran Ikram, René Höhn, Veronique Vitart, Alex W Hewitt, Konrad Oexle, Kari-Matti Mäkelä, Stuart MacGregor, Mario Pirastu, Qiao Fan, Ching-Yu Cheng, Beaté St Pourcain, George McMahon, John P Kemp, Kate Northstone, Jugnoo S Rahi, Phillippa M Cumberland, Nicholas G Martin, Paul G Sanfilippo, Yi Lu, Ya Xing Wang, Caroline Hayward, Ozren Polašek, Harry Campbell, Goran Bencic, Alan F Wright, Juho Wedenoja, Tanja Zeller, Arne Schillert, Alireza Mirshahi, Karl Lackner, Shea Ping Yip, Maurice KH Yap, Janina S Ried, Christian Gieger, Federico Murgia, James F Wilson, Brian Fleck, Seyhan Yazar, Johannes R Vingerling, Albert Hofman, André Uitterlinden, Fernando Rivadeneira, Najaf Amin, Lennart Karssen, Ben A Oostra, Xin Zhou, Yik-Ying Teo, E Shyong Tai, Eranga Vithana, Veluchamy Barathi, Yingfeng Zheng, Rosalynn Grace Siantar, Kumari Neelam, Youchan Shin, Janice Lam, Ekaterina Yonova-Doing, Cristina Venturini, S Mohsen Hosseini, Hoi-Suen Wong, Terho Lehtimäki, Mika Kähönen, Olli Raitakari, Nicholas J Timpson, David M Evans, Chiea-Chuen Khor, Tin Aung, Terri L Young, Paul Mitchell, Barbara Klein, Cornelia M van Duijn, Thomas Meitinger, Jost B Jonas, Paul N Baird, David A Mackey, Tien Yin Wong, Seang-Mei Saw, Olavi Pärssinen, Dwight Stambolian, Christopher J Hammond, Caroline CW Klaver, Cathy Williams, Andrew D Paterson, Joan E Bailey-Wilson, Jeremy A Guggenheim, CREAM Consortium
TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport Miriam Schmidts, Yuqing Hou, Claudio R Cortés, Dorus A Mans, Celine Huber, Karsten Boldt, Mitali Patel, Jeroen Van Reeuwijk, Jean-Marc Plaza, Sylvia EC Van Beersum, Zhi Min Yap, Stef JF Letteboer, S Paige Taylor, Warren Herridge, Colin A Johnson, Peter J Scambler, Marius Ueffing, Hulya Kayserili, Deborah Krakow, Stephen M King, Philip L Beales, Lihadh Al-Gazali, Carol Wicking, Valerie Cormier-Daire, Ronald Roepman, Hannah M Mitchison, George B Witman, Saeed Al-Turki, Carl Anderson, Richard Anney, Dinu Antony, Jennifer Asimit, Mohammad Ayub, Jeff Barrett, Inês Barroso, Jamie Bentham, Shoumo Bhattacharya, Douglas Blackwood, Martin Bobrow, Elena Bochukova, Patrick Bolton, Chris Boustred, Gerome Breen, Marie-Jo Brion, Andrew Brown, Mattia Calissano, Keren Carss, Krishna Chatterjee, Lu Chen, Sebhattin Cirak, Peter Clapham, Gail Clement, Guy Coates, David Collier, Catherine Cosgrove, Tony Cox, Nick Craddock, Lucy Crooks, Sarah Curran, Allan Daly, Petr Danecek, George Davey Smith, Aaron Day-Williams, Ian Day, Richard Durbin, Sarah Edkins, Peter Ellis, David Evans, I Sadaf Farooqi, Ghazaleh Fatemifar, David Fitzpatrick, Paul Flicek, Jamie Floyd, A Reghan Foley, Chris Franklin, Marta Futema, Louise Gallagher, Tom Gaunt, Daniel Geschwind, Celia Greenwood, Detelina Grozeva, Xiaosen Guo, Hugh Gurling, Deborah Hart, Audrey Hendricks, Peter Holmans, Jie Huang, Steve E Humphries, Matt Hurles, Pirro Hysi, David Jackson, Yalda Jamshidi, David Jewell, Joyce Chris, Jane Kaye, Thomas Keane, John Kemp, Karen Kennedy, Alastair Kent, Anja Kolb-Kokocinski, Genevieve Lachance, Cordelia Langford, Irene Lee, Rui Li, Yingrui Li, Liu Ryan, Jouko Lönnqvist, Margarida Lopes, Daniel G MacArthur, Mangino Massimo, Jonathan Marchini, John Maslen, Shane McCarthy, Peter McGuffin, Andrew McIntosh, Andrew McKechanie, Andrew McQuillin, Yasin Memari, Sarah Metrustry, Josine Min, Alireza Moayyeri, James Morris, Dawn Muddyman, Francesco Muntoni, Kate Northstone, Michael O’Donovan, Stephen O’Rahilly, Alexandros Onoufriadis, Karim Oualkacha, Michael Owen, Aarno Palotie, Kalliope Panoutsopoulou, Victoria Parker, Jeremy Parr, Lavinia Paternoster, Tiina Paunio, Felicity Payne, John Perry, Olli Pietilainen, Vincent Plagnol, Michael A Quail, Lydia Quaye, Lucy Raymond, Karola Rehnström, J Brent Richards, Sue Ring, Graham RS Ritchie, David B Savage, Nadia Schoenmakers, Robert K Semple
Blood pressure and mortality: using offspring blood pressure as an instrument for own blood pressure in the HUNT study Wade, K. H., Carslake, D., Nilsen, T. I. L., Timpson, N., Davey Smith, G. & Romundstad, P. R., 22 Jul 2015, In : Scientific Reports. 5, 12399
Variation in the SLC23A1 gene does not influence cardiometabolic outcomes to the extent expected given its association with L-ascorbic acid Wade, K. H., Forouhi, N. G., Cook, D. G., Johnson, P., McConnachie, A., Morris, R. W., Rodriguez, S., Ye, Z., Ebrahim, S., Padmanabhan, S., Watt, G., Bruckdorfer, K. R., Wareham, N. J., Whincup, P. H., Chanock, S., Sattar, N., Lawlor, D. A., Davey Smith, G. & Timpson, N. J., Jan 2015, In : American Journal of Clinical Nutrition. 101, 1, p.202-9
Assessment of Offspring DNA Methylation across the Lifecourse Associated with Prenatal Maternal Smoking Using Bayesian Mixture Modelling de Vocht, F., Simpkin, A. J., Richmond, R. C., Relton, C. L. & Tilling, K. M., 13 Nov 2015, In : International Journal of Environmental Research and Public Health. 12, 11, p.14461-11476
Exploring possible epigenetic mediation of early-life environmental exposures on adiposity and obesity development Richmond, R. C., Timpson, N. J. & Sorensen, T., Aug 2015, In : International Journal of Epidemiology.44, 4, p.1191-8
Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: A nested case-control study Chambers, J. C., Loh, M., Lehne, B., Drong, A., Kriebel, J., Motta, V., Wahl, S., Elliott, H. R., Rota, F., Scott, W. R., Zhang, W., Tan, S. T., Campanella, G., Chadeau-Hyam, M., Yengo, L., Richmond, R. C., Adamowicz-Brice, M., Afzal, U., Bozaoglu, K., Mok, Z. Y., Ng, H. K., Pattou, F., Prokisch, H., Rozario, M. A., Tarantini, L., Abbott, J., Ala-Korpela, M., Albetti, B., Ammerpohl, O., Bertazzi, P. A., Blancher, C., Caiazzo, R., Danesh, J., Gaunt, T. R., de Lusignan, S., Gieger, C., Illig, T., Jha, S., Jones, S., Jowett, J., Kangas, A. J., Kasturiratne, A., Kato, N., Kotea, N., Kowlessur, S., Pitkäniemi, J., Punjabi, P., Saleheen, D., Schafmayer, C., Soininen, P., Tai, E. S., Thorand, B., Tuomilehto, J., Wickremasinghe, A. R., Kyrtopoulos, S. A., Aitman, T. J., Herder, C., Hampe, J., Cauchi, S., Relton, C. L., Froguel, P., Soong, R., Vineis, P., Jarvelin, M. R., Scott, J., Grallert, H., Bollati, V., Elliott, P., McCarthy, M. I. & Kooner, J. S., 1 Jul 2015, In : Lancet Diabetes and Endocrinology. 3, 7, p.526-534
DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring Küpers, L. K., Xu, X., Jankipersadsing, S. A., Vaez, A., la Bastide-van Gemert, S., Scholtens, S., Nolte, I. M., Richmond, R. C., Relton, C. L., Felix, J. F., Duijts, L., van Meurs, J. B., Tiemeier, H., Jaddoe, V. W., Wang, X., Corpeleijn, E. & Snieder, H., 10 Apr 2015, In : International Journal of Epidemiology. 44, 4, p.1224-1237
Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children Sharp, G. C., Lawlor, D. A., Richmond, R. C., Fraser, A., Simpkin, A., Suderman, M., Shihab, H. A., Lyttleton, O., McArdle, W., Ring, S. M., Gaunt, T. R., Davey Smith, G. & Relton, C. L., 8 Apr 2015, In : International Journal of Epidemiology. 44, 4, p.1288-1304
Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an independent cohort at birth through 17 years of age Lee, K. W. K., Richmond, R., Hu, P., French, L., Shin, J., Bourdon, C., Reischl, E., Waldenberger, M., Zeilinger, S., Gaunt, T., McArdle, W., Ring, S., Woodward, G., Bouchard, L., Gaudet, D., Smith, G. D., Relton, C., Paus, T. & Pausova, Z., 1 Jan 2015, In : Environmental Health Perspectives. 123, 2, p.193-199
Self-management for people with poorly controlled epilepsy: Participants' views of the UK Self-Management in epILEpsy (SMILE) program Laybourne, A. H., Morgan, M., Watkins, S. H., Lawton, R., Ridsdale, L. & Goldstein, L. H., 28 Sep 2015, In : Epilepsy and Behavior. 52, Pt A, p.159-164