Pocket feature shared by deadly coronaviruses could lead to pan-coronavirus antiviral treatment23 November 2022Scientists have discovered why some coronaviruses are more likely to cause severe disease, which has remained a mystery, until now. Researchers of the University of Bristol-led study, published in Science Advances today [23 November], say their findings could lead to the development of a pan-coronavirus treatment to defeat all coronaviruses—from the 2002 SARS-CoV outbreak to Omicron, the current variant of SARS-CoV-2, as well as dangerous variants that may emerge in future.
New trial to assess whether rapid tests reduce antibiotic prescribing for respiratory infections in primary care23 November 2022A new randomised controlled clinical trial, led by the University of Bristol, will investigate whether rapid microbiological 'point-of-care' tests for respiratory infections could reduce antibiotic prescribing in primary care, thanks to funding of £1.6 million by the National Institute for Health and Care Research (NIHR). The tests, which are carried out in GP surgeries rather than sent to a laboratory, detect the presence of viruses and some bacteria, with results available on the same day.
This year’s Doctoral Prize winners are…18 November 2022Each year the University of Bristol picks six outstanding theses – one from each faculty – from hundreds of fascinating submissions by doctoral researchers in the last year. This year’s winners each receive £500 and a special certificate.
Films explain how we can find solutions for a healthier future1 November 2022Climate change is one of the biggest health threats facing humanity. It is already affecting our health, and these impacts are likely to increase. A series of short films developed by the University of Bristol’s Elizabeth Blackwell Institute for Health Research and Cabot Institute for the Environment explain how the health of our planet is linked to human health, and how research at Bristol will help us to understand these complex and interwoven issues.
Discovery of Er Blood Group System26 September 2022Scientists from the University of Bristol and NHS Blood & Transplant (NHSBT) have discovered a rare new blood group system. The findings, published in Blood, the journal of the American Society of Hematology, also solve a 30-year mystery.
Increase in non-COVID-19 respiratory infections predicted this winter9 August 2022An increase in the number of non-COVID-19 respiratory infections should be expected this winter, say scientists. The warning comes following the results of a new study, published in The Lancet Regional Health – Europe, which found that over 55% of respiratory disease hospitalisations during the pandemic’s peak were caused by non-SARS-CoV-2 infections.
New report finds stark impact of newborn illness on mortality throughout childhood14 July 2022New evidence has found a link between poor health as a newborn and mortality up to the age of ten. The new report from England’s National Child Mortality Database (NCMD), led by the University of Bristol, shows of the 4,829 children aged ten and under who died in England between 2019 and 2021, 72 per cent were found to have required additional care in the neonatal period.
Impact of exposure to COVID-19 infection early in life on a child’s brain development28 June 2022More than 650,000 babies are born every year in the UK, and during the pandemic some of them will have been exposed to SARS-CoV-2, the coronavirus which causes COVID-19. A national study, funded by the charity Action Medical Research, will investigate the long-term impact of exposure to SARS-CoV-2 in the womb or shortly after birth.
Infectivity of airborne SARS-CoV-2 could decrease by 90% within 20 minutes of exhalation28 June 2022The SARS-CoV-2 virus can lose 90% of infectivity when in aerosol particles within 20 minutes, according to new University of Bristol findings. The study, published in the journal of the Proceedings of the National Academy of Sciences (PNAS), is the first to investigate the decrease in infectivity of SARS-CoV-2 in aerosol particles over periods from seconds to a few minutes. The aim of the study was to explore the process that could change viral infectivity over short timescales following exhalation.
Vaccines: Discovery to Uptake event, 21 June 202222 June 2022The University of Bristol's Infection and Immunity Network, supported by the Elizabeth Blackwell Institute, hosted its 11th annual symposium in the Geographical Sciences Building on 21 June 2022. Jointly hosted with the Bristol Vaccine Centre, the event presented a narrative of the vaccine pathway, from initial cellular work through to delivery in communities.
Novel host cell pathway hijacked during COVID-19 infection14 June 2022An international team of scientists, led by the University of Bristol, has been investigating how the SARS-CoV-2 virus, the coronavirus responsible for the COVID-19 pandemic, manipulates host proteins to penetrate into human cells. After identifying Neuropilin-1 (NRP1) as a host factor for SARS-CoV-2 infection, new findings published in the journal of the Proceedings of the National Academy of Sciences (PNAS) today [14 June] describe how the coronavirus subverts a host cell pathway in order to infect human cells.
The right moisturiser for children with eczema is the one that they like to use24 May 2022The Best Emollients for Eczema trial has found that no one type of moisturiser is better than another. This study, the first in the world to directly compare different types of moisturisers, highlights the importance of patient education and choice when deciding which moisturisers to use for children with eczema. The results from the National Institute for Health and Care Research (NIHR) funded study are published in The Lancet Child & Adolescent Health and British Journal of General Practice today [24 May].
People were hesitant rather than opposed to the COVID-19 vaccine11 May 2022A study that explored the attitudes of vaccine hesitant adults in the UK towards uptake of the COVID-19 vaccine found that participants were hesitant rather than opposed to the vaccine. They had questions about their need for, and the safety and efficacy of the vaccine. Concerns were exacerbated by a lack of trust in government and misunderstanding of science, the University of Bristol-led study found.
International siblings study sheds new light on the nature of the genetics of disease10 May 2022Genetic studies aim to find regions of the genome that associate with diseases or other outcomes. A new study has shown that for social traits these genetic effects are due to a mixture of direct effects (e.g. biological effects of DNA), and indirect effects (e.g. family or social environment). Whereas biological traits are mainly driven by direct effects.
Childhood obesity increases risk of type 1 diabetes29 April 2022Being overweight in childhood increases the risk of developing type 1 diabetes in later life, according to the findings of a new study that analysed genetic data on over 400,000 individuals. The study, co-led by researchers from the Universities of Bristol and Oxford and published today in Nature Communications, also provides evidence that being overweight over many years from childhood influences the risk of other diseases including asthma, eczema and hypothyroidism.