Virus-specific T cells constitute an essential line of defence during viral infection and both an impaired or exacerbated T cell response are detrimental to the host. We are interested in understanding how T cells contribute to protective immunity and/or immunopathology during viral infection, particularly in the context of dengue virus infection, and more recently in COVID-19. Understanding these mechanisms is critical for the development of effective vaccines and immunomodulatory therapeutics.  

We collaborate with scientists and clinicians at the Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City in Vietnam, the National Centre for Infectious Diseases (NCID) in Singapore, Duke-NUS Medical School in Singapore and North Bristol NHS Trust in Bristol, UK.