Funding and references

Mysmile is a study investigating whether improving oral health can slow memory loss.

Funding

The Mysmile study is funded by the National Institute for Health and Care Excellence (NIHR) Research for Patient Benefit, NIHR number 203048.

Ethical review

This study has been reviewed and given favourable ethical approval by National Research Ethics Service: West of Scotland Research Ethics Service (WoSRES), IRAS ID 315223.

Selected references

  • World_Health_Organization, World Health Organization Fact Sheet for Dementia https://www.who.int/news-room/fact-sheets/detail/dementia 2020 
  • Kinney, J.W., et al., Inflammation as a central mechanism in Alzheimer's disease. Alzheimers Dement (N Y), 2018. 4: p. 575-590.    
  • Moir, R.D., R. Lathe, and R.E. Tanzi, The antimicrobial protection hypothesis of Alzheimer's disease. Alzheimers Dement, 2018. 14(12): p. 1602-1614.  
  • Dansokho, C. and M.T. Heneka, Neuroinflammatory responses in Alzheimer's disease. J Neural Transm (Vienna), 2018. 125(5): p. 771-779.  
  • Hajishengallis, G., T. Chavakis, and J.D. Lambris, Current understanding of periodontal disease pathogenesis and targets for host-modulation therapy. Periodontol 2000, 2020. 84(1): p. 14-34. 
  • Emery, D.C., et al., Comparison of Blood Bacterial Communities in Periodontal Health and Periodontal Disease. Front Cell Infect Microbiol, 2020. 10: p. 577485. 
  • Hirschfeld, J., Chapple, ILC (Editors), Periodontitis and Systemic Diseases: Clinical Evidence and Biological Plausibility. Quintessence Publishing 2021. ISBN 978-1-78698-100-4.  

 

 

 

 

 

 

Contact

If you would like to take part, or have questions, please get in touch:

Miss Nikki Hellin, email nikki.hellin@bristol.ac.uk or telephone  07773 579130

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