There is an extensive body of cancer research across two faculties (Biomedical Sciences and Health Sciences) at the University of Bristol and at the University of West of England, which is focused on the role of individual proteins and protein families in cancer development and metastasis. We use models ranging from tissue culture through to the translucent zebrafish larvae and mouse work in order to understand fundamental principles of cancer cell proliferation, migration and interaction with immune cells.

Increasingly, the work involves close collaboration with genetic epidemiologists and clinical and population scientists and is particularly taking advantage of the availability of unique local tissue resources and banks (eg prostate).

The research offers broad opportunities for clinical engagement across a number of cancer diagnoses; most specifically this is ongoing in prostate and colon cancer, but includes further activities and opportunities in breast, Wilms, neuroblastoma, glioma, lung, upper gastro-intestinal, head and neck, and neuroendocrine tumours.

Further information

As a multidisciplinary network cancer research at Bristol draws expertise from across the University and beyond. You can learn more about the work being carried out in specific groups by visiting their research pages:

• Colorectal tumour biology group
• Cancer Epigenetics Lab
• Insulin-like Growth Factors and Metabolic Endocrinology Group (IMEG)
• Brain Tumour Research Centre
• Integrative Cancer Epidemiology Programme
• Immune response and tumour initiation
• Lifecourse Epidemiology and Population Oral Health