The Elizabeth Blackwell Institute's Bristol Cancer Research Network is delighted to be hosting its third annual Early Career Researchers' (ECRs) symposium on 18 June 2024.

The event is open to all and aims to foster the creation of new research directions, new ways of working, new ways to support and enable our academic and clinical communities, and new learning experiences. 

Call for abstracts: The call for abstracts is now CLOSED

Registration: Registration is now CLOSED

Programme:

10.00-10.05	Introduction and Welcome				Jonathan Aning, Consultant Urological Surgeon, Bristol Urology Institute, North Bristol NHS Trust
	Session 1
10.05-10.20	Benedita Deslandes	PhD student	Bristol Medical School: Population Health Sciences	University of Bristol	A transcriptome-wide Mendelian randomization study assessing the causal role of CD4+ T cell gene expression profiles in colorectal cancer development
10.20-10.35	Raisha Gibbs	PhD student	Bristol Medical School	University of Bristol	Investigating the Role of Fusobacteria in malignancies
10.35-10.50	Olympia Dimopoulou	PhD student (CRUK ICEP)	Bristol Medical School: Population Health Sciences	University of Bristol	The role of sex-hormones in prostate cancer aetiology
10.50-11.05	Zhaozhen Xu	Senior Research Associate	Bristol Medical School: Population Health Sciences	University of Bristol	Automating Screening of Studies for Systematic Reviews Using a Large Language Model
11.05-11.30	Ed Roberts	Senior Lecturer	School of Cancer Sciences, CRUK Scotland Institute	University of Glasgow	Failure to recruit lymph node resident cDC1 during anti-tumour CD8 T cell priming results in poorly functional T cell responses
11.30-13.30	Lunch and Poster Session
	Session 3
13.30-13.45	Leila Ellis	NIHR Academic Clinical Fellow	Bristol Medical School: Population Health Sciences	University of Bristol	Use of Polygenic Risk Scores in Childhood Cancer: Scoping Review and Project Proposal
13.45-14.00	Liz Joseph	IMT1	Bristol Royal Infirmary	University Hospitals Bristol and Weston NHS Foundation Trust	Real world experience of bispecific fusion protein in patients with metastatic uveal melanoma: Can we deliver?
14.00-14.15	Matthew Lee	Postdoctoral Researcher		International Agency for Research on Cancer, World Health Organisation	Proteomic analyses of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition
14.15-14.30	Jinyan Duan	PhD student	School of Physics	University of Bristol	A Monte Carlo simulation of DNA damage in BNCT radiotherapy
14.30-14.55	Simon Buczacki	Richard Blackwell Professor of Colorectal Surgery	Nuffield Department of Surgical Sciences	University of Oxford	Bad surgeon, bad scientist? A journey through surgery and cancer biology
14.55-15.00	Closing remarks

Posters: (more will be added as confirmations come back)

• Abu Sabah, Lujin (PhD student, School of Physics, University of Bristol): A novel delivery method for α therapy
• Al Husein, Nour (Senior Research Associate,  Bristol Medical School): Co-production of a physical activity intervention in South-Asian men with prostate cancer or at risk of prostate cancer
• Alhadrami, Mai (PhD student, Bristol Medical School): The role of the amyloid precursor protein processing pathway in the proliferation of prostate cancer cells
• Ballisat, Laura (PhD student, School of Physics, Bristol): Simulation of cell cycle compaction on DNA strand break induction
• Belfield, Katherine (PhD student, School of Cellular and Molecular Medicine, Bristol): Using 5-ASA for the prevention of sporadic colorectal cancer
• Bojko, Jodie (Research Associate, Cancer Epigenetics Lab, School of Cellular and Molecular Medicine, Bristol): PRMT5 regulates cancer cell fitness through spliceosomal, epitranscriptomic and metabolic mechanisms
• Coakley, Stephanie (Data Manager/Research Assistant, Centre for Trials Research, Cardiff University): Are data minimisation principles applied through the use of data justification categories on trial metadata? An analysis in the SCC-AFTER trial
• Compton, Hannah (FY1 Doctor and project proposal lead, University Hospitals Bristol and Weston NHS Foundation Trust): Cervical screening accessibility for healthcare staff: a call to action
• De Sio, Chiara (Senior Research Associate, School of Physics, Bristol): A Geant4 study of the DNA damage in Targeted Alpha Therapies using 211At
• Duru, Kelvin (Medical Student, St Bartholomews and London Medical School): Inequalities in Cancer Screening Participation: Insights from Under-Represented Communities
• Frayne, Ceri (Senior Data Manager [Cancer Division] & Research Associate, Centre for Trials Research, Cardiff University): Piloting a standardised variable syntax in a new skin cancer trial: SCC-AFTER     
• Gill, Emily (PhD student, Bristol Medical School): Identifying the role of PLEKHS1 in cancer
• Goudswaard, Lucy (Senior Research Associate, Bristol Medical School): Investigating the causal role of circulating proteins in multiple myeloma
• Grant, Tressan (PhD student, Cellular and Molecular Medicine, Bristol): The regulation of tumour cell cytolysis by cancer associated fibroblasts
• Growcott, Siona (Clinical oncology specialist registrar [ST5], Department of Clinical Oncology, Bristol Haematology and Oncology Centre, University Hospitals Bristol and Weston NHS Foundation Trust): Patient reported outcome measures of head and neck cancer patients treated with curative intent radiotherapy within the Head and Neck 5000 cohort
• Hazelwood, Emma  (PhD student, Bristol Medical School): Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes
• Hobson, Lisa (PhD student, MRC Integrative Epidemiology Unit, Bristol Medical School): Using human genetics to identify novel biomarkers for enhanced prediction and early detection of cancer
• Hoskin, Ashley (PhD student, School of Cellular and Molecular Medicine, Bristol): Is 5-aminosalicylic acid (5-ASA) the new aspirin?
• Irving, Alys (Research Assistant/Data Manager, Centre for Trials Research, Cardiff University): VALTIVE1: RECIST data: challenges and methodology in the VALTIVE1 study     
• Li, Haonan (PhD student, Bristol Medical School): Repurposing Drugs for the Prevention and Treatment of Prostate Cancer
• Markham, Philip (Data Manager, Centre for Trials Research, Cardiff University): The impact of a change in TMN staging classification edition during the SCOPE2 clinical trial and process for correction to ensure consistency
• Markham, Philip (Data Manager, Centre for Trials Research, Cardiff University): A specialised REDCap database for PICCOS, a complex randomised clinical trial with a multitude of treatment modalities
• Markham, Philip (Data Manager, Centre for Trials Research, Cardiff University): Utilising repeating (‘cloned’) forms to minimise workload required when building, editing or testing clinical trial databases
• Martin, Charlotte (Research Assistant/ Data Manager, Centre for Trials Research,  Cardiff University): Management of a Complex Dataset
• Shi, Yuyao (PhD student, School of Physics, Bristol): Non-homologous end joining (NHEJ) repair mechanism and DSB End motion in silico modelling
• Spiga, Francesca (Senior Research Associate, Bristol Medical School): The effects of sunlight exposure on mortality: a systematic review of epidemiological studies
• Squires , Rebecca (ACF SpR Medical Oncology, Bristol Medical School): Using Mendelian randomization estimates to calculate the global burden of endometrial cancer attributable to overweight and obesity
• Su, Xiaoyu (PhD student, Bristol Medical School): Investigating the role of ERβ and IGFBP5 in the inhibitory effects of oestrogen receptor modulators  in colon cancer
• Waterfield, Scott (PhD student, Bristol Medical School): DNA methylation estimates of protein abundance and aging to determine cancer risk from prediagnostic blood