Hosted by the Bristol BioDesign Institute

Site specific diagnostics and effective, localized therapy delivery remain challenge tasks in today’s medicine. To address this need, my laboratory develops micro- and nanosystems that respond to disease-specific biochemical cues or non-invasive external stimuli like magnetic or acoustic energy such that they focus their action at the site of disease. In this talk, I describe a synthetically engineered system that is designed to acoustically report information about local proteolytic activity as disease biomarker. Further, I will show how an individual, bacteria-inspired microrobot and swarms of living magnetic bacteria can be powered with magnetic fields to locally enhance transport of nanodrug shuttles to tumor tissues. Lastly, I will present how these bacteria can be further engineered to function as controllable therapeutic vectors themselves. 

Zoom webinar link: https://bristol-ac-uk.zoom.us/j/92204040491
Slido meeting number: #599138

Further details on https://www.bristol.ac.uk/biodesign-institute/events/2022/webinar---simone-schurle-finke.html.