Medicines and prescribing
The Medicines and Prescribing research group at the Centre for Academic Primary Care (CAPC) is a small but rapidly expanding multidisciplinary team of researchers. We have broad interests covering a range of topics related to the rational and safe use of medicines in primary care.
Areas of interest include:
- medicines optimisation
We also have active collaborations with researchers at the Universities of Cambridge, Nottingham, Oxford and Dundee, and support the provision of undergraduate teaching on pharmacology and therapeutics at Bristol Medical School.
Medicines and prescribing facts
Medications are the main therapeutic intervention offered by clinicians to improve health, with most prescribing occurring in primary care.
Over 1 billion items are dispensed annually in primary care in England alone, and prescribing accounts for the biggest proportion of non-staff expenditure by the NHS.
Over half of patients in their 70s are on at least four regular medications.
Barbara has a PhD in social and cultural history, and provides administrative support for the group.
Tegan is an academic administrator supporting Rupert Payne and the Medicines and Prescribing Group.
Shoba is a Senior Research Associate with diverse experience within primary care research. She is currently leading a project investigating prescription medication sharing by primary care patients. Her research interests include medicines optimisation, patient safety, multimorbidity and systematic reviews.
Rachel is an experienced epidemiologist and supports broader work in the Department of Population Health Sciences using the CPRD database. She is involved with several pharmacoepidemiological studies, including leading a project investigating the effectiveness of cardiovascular preventative treatment in patients with multimorbidity.
Polly is a GP and NIHR In-Practice Fellow interested in multimorbidity, polypharmacy and deprescribing. She and Prof Chris Salisbury developed and validated the 'Multimorbidity Treatment Burden Questionnaire' - a widely used tool. She has applied for a NIHR doctoral fellowship focused on the characteristics and unmet care needs of housebound patients.
Debbie is a Research Fellow with longstanding and diverse research experience and expertise within a primary health care setting. Her research interests include medicines optimisation and users' experience of medication review.
Cindy is an experienced qualitative researcher specialising in process evaluation in trials of primary care interventions for people with multimorbidity. She has a particular interest in person-centred care and patient involvement in research.
- Roxanne Parslow
Rupert is a GP and Clinical Pharmacologist, and Consultant Senior Lecturer. He has particular interests in polypharmacy and electronic health records, and is chief investigator for the IMPPP trial. He co-authored the influential King's Fund report on polypharmacy.
At Bristol Medical School his research interest is mainly on the organization of healthcare. Research keywords: primary care, continuity of care, unscheduled healthcare use, medicine prescribing, routine/administrative data, survey data, quantitative research.
- IMPPP: Improving Medicines use in People with Polypharmacy in Primary Care. Payne RA, Salisbury C, Round J, Morris R, Jameson C, Dreischulte T, Guthrie B, Chew-Graham C. Funder: NIHR Health Services and Delivery Research (2018-2022)
- Developing a measure of inappropriate polypharmacy in primary care. Payne RA, Hay A, Morris R, MacLeod J, Avery A, Rodgers S, Burt J, Campbell S. Funder: NIHR School for Primary Care Research (2016-2018)
- Impact of hospital admission upon patterns of primary care prescribing. Payne RA, Purdy S, Morris R. Funder: NIHR School for Primary Care Research (2016-2018)
- The effectiveness of CVD preventative treatment in a multi-morbid population. Denholm R, Macleod J, Payne RA, Morris R, Davies N. Funder: NIHR School for Primary Care Research (2017-2019)
- What is the role of genetics in primary care? Payne R. Funder: NIHR Evidence Synthesis Working Group. Funder: NIHR School for Primary Care Research (2017-2020)
- Patient experiences and perceptions of medication review in general practice. McCahon D, Horwood J, Payne RA, Duncan P. Funder: RCGP SFB (2018-2019)
- Using national administrative data to evaluate new models of primary care prescribing. Payne RA, Denholm R, McCahon D, Kontopantelis E, Rodgers S. Funder: NIHR School of Primary Care Research (2018-2019)