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The Mathematics of Disease

18 December 2015

Medical research and advanced mathematics are usually considered separate disciplines. But for one WUN collaboration, bringing maths and biology together could hold the key to understanding how cells in the human body signal to each other, and might potentially unlock the secrets of a range of non-communicable diseases.

Cell signalling in the body is the result of a complex interaction of feedback loops, since each of the body’s processes has its own unique timescale – from neurons that fires in milliseconds to eating, sleeping and reproductive cycles. The team of experts from three WUN universities – including Professor Andrew Randall from the University of Bristol – is investigating how these complicated feedback loops can lead to problems in cell signalling, causing conditions such as Alzheimer’s disease, diabetes, epilepsy and asthma. 

 

Further information

Read more about the WUN Mathematics of Non-communicable Diseases: Understanding failure of cell signalling project.