| 12:00 - 13:00 | Arrival and registration / poster set-up |
| 13:00 - 13:15 | Welcome and introduction from Professor Geoff Burnstock |
Symposia 1 - P2X7: muscle and bone
| 13:15 - 14:00 | Iolanda D'Alimonte (University of Chieti, Italy) Stability and Plasticity of Synapses: a Molecular Movie |
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| 14:00 - 14:15 | Magdalena Adamczyk (University of Cardiff /Sheffield, UK) The emerging role of P2X7 receptor in mediating subchondral bone changes during mechanically induced osteoarthritis |
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| 14:15 - 14:30 | Jessal J Patel (Royal Veterinary College, London, UK) Extracellular nucleotides act via different mechanisms to inhibit bone mineralisation and vascular calcification; |
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| 14:30 - 14:45 | C. Young(University of Portsmouth, UK) P2X7 and skeletal muscle pathology; |
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| 14:45 - 15:15 | Tea and coffee |
Symposia 2 - P2X7: muscle and bone
| 15:15 - 16:00 | Maria Pia Abbracchio (University of Cambridge, UK) GPR17 and Neurodegeneration |
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| 16:00 - 16:15 | Guy Brown (UniversitK) Blocking the microglial P2Y6 receptor prevents neurodegeneration |
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| 16:15 - 17:00 | Elsa Fabbretti (University of Nova Gorica, Slovenia) Molecular characterization of an ATP keeper in sensory neurons |
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| 17:00 - 17:45 | Professor Julian Paton (University of Bristol, UK) Rescuing afferent dysfunction with novel purinergic antagonists as a therapeutic strategy in disease |
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| 17:45 - 19:30 | Poster session with wine | |
| 20:00 | Dinner followed by drinks at bar |
Self-service breakfast from 07:30
Symposia 3 - P2X7 – signalling and pathology
| 09:00 - 09:45 | Francesco Di Virgilio (University of Ferrara, Ferrara, Italy) P2X7- the damage sensing receptor |
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| 09:45 - 10:00 | Elsa Rottoli (University of Milan) Signaling and metabolic reprogramming of effector/memory T cells by purinergic P2X7 receptor ; |
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| 10:00 - 10:15 | Elena Adinolfi (University of Ferrara, Italy) P2X7 receptor modulates immune responses and extracellular ATP levels in experimental models of cancer |
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| 10:15 - 10:30 | S. Dayl (University of Leicester, UK) Modelling binding modes of the P2X7R selective inhibitor AZ10606120 |
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| 10:30 - 11:00 | Tea and Coffee |
Symposia 4 - P2Y receptor pharmacology (sponsored by Astra Zeneca)
| 11:00 - 11:45 | Kenneth A. Jacobson (National Institute Health, Bethesda, USA) P2Y receptor pharmacology and structure function |
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| 11:45 - 12:00 | Riyaad Aungraheeta (University of Bristol) Therapeutic significance of P2Y12 receptor traffic in platelets – influence of antiplatelet drugs |
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| 12:00 - 12:45 | Rob Storey (University of Sheffield, UK) P2Y12 receptor antagonism-platelets and beyond |
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| 12:45 - 13:00 | Richard Amison (Kings College London) P2Y1 and P2Y14 receptors mediates LPS induced pulmonary leukocyte recruitment in mice |
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| 13:00 - 13:45 | Lunch |
Symposia 5 - Purines function: from whole animal to organelle biology
| 13:45 - 14:00 | Chiara Giacomelli (University of Pisa, Italy) Low TNF-α concentration modulates the A2BAR mediated mesenchymal stem cell differentiation. |
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| 14:00 - 14:45 | Carolina Pellegrini (University of Pisa, Italy) Involvement of A2B receptors in the enteric dysmotility associated with high fat diet-induced obesity in mice |
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| 14:45 - 15:00 | Giorgio Fois (University of Ulm, Germany) ATP from lamellar bodies facilitates surfactant secretion |
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| 15:00 - 15:15 | Sin Lih Tan (University of Cambridge) Lysosome P2X4 receptors amplify intracellular Ca2+ signals and promote lysosome fusion |
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| 15:15 - 15:30 | Best poster and short talk prize awards and goodbyes |
