Professor Vikki Wylde
B.Sc.(Bristol), PhD
Current positions
Professor of Musculoskeletal Health
Bristol Medical School (THS)
Contact
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Research interests
I am a health services researcher with an interest in improving the health and wellbeing of people living with chronic musculoskeletal conditions. I conduct research that spans the translational pathway and impacts on patient care through informing NICE guidance and changing NHS practice. My research aims to improve patients’ outcomes and experiences of interventions for musculoskeletal pain, with a particular focus on evaluating interventions to optimise outcomes after orthopaedic surgery, such as hip and knee replacement. I am committed to ensuring that health research is inclusive, through involvement of patients and communities in all stages of the research process.
I currently lead the RADICAL trial, a NIHR HTA-funded randomised trial evaluating the clinical and cost-effectiveness of radiofrequency denervation for chronic low back pain. I am also Chief Investigator on the Joint PREP study, a NIHR RfPB-funded feasibility study for a randomised trial evaluating pre-operative exercise and nutrition for frail patients undergoing hip and knee replacement. I am Joint Lead Applicant on a RfPB-funded project to develop a care plan for patients having knee replacement. Other NIHR-funded research that I am involved in covers topics such as patellar resurfacing, implant type for hip replacement, injections for osteoarthritis, sleep and implementing research findings into NHS practice. I am Co-Theme Lead for Surgical and Orthopaedic Innovation in the Bristol Biomedical Research Centre.
For the MSc in Orthopaedic Research Methods and Evidence-Based Medicine, I am Lead for the Research Projects Unit. In the iBSc in Clinical Sciences, I co-lead a Unit on clinical research methods in chronic diseases.
Projects and supervisions
Research projects
NIHR Programme Development Grants (NIHR202943) Infection and Orthopaedic Management: Mobilising evidence into practice
Principal Investigator
Role
Co-Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/07/2021 to 30/06/2023
Feasibility study for a randomised controlled trial of one-stage or two-stage surgery for prosthetic knee infection
Role
Co-Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/07/2020 to 01/07/2022
RecUrrent Intra-articular Corticosteroid injections in Osteoarthritis; the RUbICOn study
Principal Investigator
Role
Principal Investigator
Description
Osteoarthritis is a condition that causes joints to become painful and stiff, it is a common cause of pain
and disability. Management of osteoarthritis involves reducing pain and maintaining function. Simple…Managing organisational unit
Bristol Medical School (THS)Dates
01/03/2020 to 31/08/2022
NIHR Health Technology Assessment (NIHR127457) Radiofrequency denervation for chronic and moderate to severe low back pain: The RADICAL trial.
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/01/2020 to 31/12/2024
Thesis supervisions
Publications
Recent publications
01/06/2024Prevalence and patterns of neuropathic pain in people with chronic post-surgical pain after total knee arthroplasty
The bone & joint journal
REST
BMJ Open
The clinical and cost-effectiveness of elective primary total knee replacement with PAtellar Resurfacing compared to selective patellar resurfacing
Bone & joint open
Is it possible to predict which patients are most likely to benefit from intra-articular corticosteroid injections? A systematic review.
International Journal of Rheumatic Diseases
Support and Treatment After Knee Replacement (STAR) Training Package
Thesis
The role of pre-operative pain sensitisation in chronic pain after knee replacement
Supervisors
Award date
01/01/2010