Professor Varinder Aggarwal
B.A., Ph.D.(Cantab.), F.R.S.
Current positions
Alfred Capper Pass Chair of Chemistry
School of Chemistry
Contact
Press and media
Many of our academics speak to the media as experts in their field of research. If you are a journalist, please contact the University’s Media and PR Team:
Research interests
My research interests include; the development of new catalytic processes for asymmetric synthesis; the development of chiral carbenoids and their use and subsequent applications in catalysis and synthesis; the development of new methodology and its applications in synthesis; total synthesis of biologically important targets.
Professor Aggarwal is a supervisor in the EPSRC Centre for Doctoral Training in Chemical Synthesis
Projects and supervisions
Research projects
Conformation, Automation and Applications of Polyborons in Synthesis
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/10/2023 to 30/09/2028
PROTACs as a novel approach to target tyrosine kinases for degradation in human platelets
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/10/2023 to 30/09/2026
Hong Chen Shen MSCA PF: Asymmetric Carboamination of Alkenylboronates
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/06/2023 to 31/05/2025
Catalysis
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/08/2022 to 31/07/2024
PGI2-PAH CIC project-additional funding
Principal Investigator
Managing organisational unit
School of ChemistryDates
01/07/2022 to 30/06/2023
Thesis supervisions
Investigations Towards the Synthesis and Reactivity of 1,2-Bis(Boronic Esters) and its Application Towards the Total Synthesis of Bahamaolide A
Supervisors
Lithiation and Borylation of Secondary O- and S- Substituted Hindered Benzoates
Supervisors
Synthesis of Borylated Cyclobutanes via a Strain-Release 1,2-Metallate Rearrangement
Supervisors
Synthesis of Functionalised Cyclopropanes from Carboxylic Acids via a Radical Addition–Polar Cyclisation Cascade
Supervisors
Lithiation-Borylation Methodology: New Classes of Metal Carbenoid Precursors for the Iterative Homologation of Boronic Esters
Supervisors
New Developments in Organoboron Incorporation, Homologation and Functionalization
Supervisors
Design, Synthesis and Characterisation of Novel Linker Chains under Conformational Control for PROTAC Drug Discovery
Supervisors
Combining computational modelling, NMR spectroscopy and assembly-line synthesis for studying molecular conformations
Supervisors
Decarboxylative Radical Additions to Vinyl Boronic Esters
Supervisors
Interrupted Zweifel Olefination
Supervisors
Publications
Recent publications
05/06/2024Difluorinated thromboxane A2 reveals crosstalk between platelet activatory and inhibitory pathways by targeting both the TP and IP receptors
British Journal of Pharmacology
Simultaneous Stereoinvertive and Stereoselective C(sp3)–C(sp3) Cross-Coupling of Boronic Esters and Allylic Carbonates
Journal of the American Chemical Society
Application of Enantioselective Sulfur Ylide Epoxidation to a Short Asymmetric Synthesis of Bedaquiline, a Potent Anti-Tuberculosis Drug
Organic Letters
Conformationally Controlled sp3‐Hydrocarbon‐Based α‐Helix Mimetics
Angewandte Chemie - International Edition
Convergent Deboronative and Decarboxylative Phosphonylation Enabled by the Phosphite Radical Trap “BecaP”
Journal of the American Chemical Society