Professor Saadeh Suleiman
PhD, DSc, FIACS, FESC, FRSB, FPhysiol
Expertise
Current positions
Professor of Cardiac Physiology
Bristol Medical School (THS)
Contact
Press and media
Many of our academics speak to the media as experts in their field of research. If you are a journalist, please contact the University’s Media and PR Team:
Research interests
Current Research Projects (basic science/translational/clinical):
- Role of cyclic AMP/PKA/Epac signalling in cardioprotection.
- RIPC Clinical Trial: A two-centre randomised controlled trial investigating the effect of remote ischaemic preconditioning on biomarkers of stress and injury-related signalling in patients having isolated coronary artery bypass grafting or aortic valve replacement using cardiopulmonary bypass.
- Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass: Propofol cardioplegia for myocardial protection randomised controlled trial: The Prompt2 Study.
- The aged heart and diet: vulnerability to cardiac insults.
- Cardiac remodelling post infarction during postnatal development.
- Effect of inflammation on cardiac remodelling post infarction.
- Hyertension induced cardiac remodelling.
- The cardio-protective efficacy of cardioplegic solution supplemented with Sildenafil in neonatal pig model of cardiopulmonary bypass and cardioplegic arrest.
Projects and supervisions
Research projects
The role of cardiac exchange protein directly activated by cAMP during postnatal development
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
03/02/2016 to 02/02/2019
Role of cyclicAMP/PKA/Epac signalling in cardioprotection
Principal Investigator
Managing organisational unit
Bristol Medical School (THS)Dates
01/12/2015 to 31/12/2017
Thesis supervisions
Simultaneous Activation of PKA and Epac is Cardioprotective in Neonatal and Adult hearts
Supervisors
Cardiac Survival Signalling, Oxidative Stress & Reperfusion Injury during Postnatal Development
Supervisors
Development and characterisation of a porcine closed chest model of acute myocardial infarction for cells, drugs, and tissue engineering applications.
Supervisors
Post-translational modifications in mitochondrial dynamics
Supervisors
Decellularised Veins as a Scaffold for in situ Vascular Tissue Engineering
Supervisors
Characterisation of post ischaemic cardiac remodelling in rodent and porcine models of cardiac injury
Supervisors
Cardiac remodelling following myocardial infarction and the cardioprotective efficacy of adrenergic stimulation against reperfusion injury in healthy and failing hearts
Supervisors
Mechanisms underlying the protective effects of cAMP in cardiac fibrosis
Supervisors
Cardiac Remodelling and Vulnerability to Ischaemia/Reperfusion Injury with Ageing and High-Fat Diet
Supervisors
Investigating the link between sympathetic nerve activation and inflammation in the progression of hypertensive heart disease
Supervisors
Publications
Recent publications
11/01/2024Corrigendum
Frontiers in Surgery
Efficacy of propofol-supplemented cardioplegia on biomarkers of organ injury in patients having cardiac surgery using cardiopulmonary bypass
Perfusion
Patterns of cytokine release and association with new onset of post-cardiac surgery atrial fibrillation
Frontiers in Surgery
The effect of cardioplegic supplementation with sildenafil on cardiac energetics in a piglet model of cardiopulmonary bypass and cardioplegic arrest with warm or cold cardioplegia
Frontiers in Cardiovascular Medicine
Related people
Dr Igor Khaliulin
Research Fellow
Bristol Medical School (THS)
Professor Gianni Angelini
BHF Professor of Cardiac Surgery and Director
Bristol Medical School (THS)
Professor Sarah George
Dean of the Faculty of Health Sciences
Health Sciences Faculty Office
Professor Massimo Caputo
Professor of Congenital Heart Surgery
Bristol Medical School (THS)
Professor Raimondo Ascione
Professor of Cardiac Surgery and Translational Research and Director of TBRC
Bristol Medical School (THS)