The major aim of my research is to develop neuro-regenerative therapies for people with currently untreatable progressive neurological disease.

Cell therapies hold much promise for the treatment of human diseases. Experimental findings in both humans and models of neurodegenerative disease have shown that adult stem cells derived from the bone marrow, commonly known as bone marrow or blood stem cells, can protect or even repair injured nerve cells. Through employing experimental studies, ranging from basic neuroscience to translational clinical trials, my research explores the medical use of bone marrow stem cell transplantation and mobilisation techniques as a regenerative therapy for people with Friedreich’s ataxia and cerebellar disorders.