
Professor Golam Khandaker
MBBS, MPhil, PhD, FRCPsych
Current positions
Professor of Psychiatry and Immunology and MRC Investigator
Bristol Medical School (PHS)
Contact
Press and media
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Research interests
Golam Khandaker is Professor of Psychiatry at Bristol Medical School, Head of Immunopsychiatry and Experimental Medicine Programme at the MRC Integrative Epidemiology Unit, and Honorary Consultant Psychiatrist at the Avon and Wiltshire Mental Health Parthership NHS Trust. Golam's research focuses on identifying and validating novel immunological mechanisms and potential treatment targets for major psychiatric disorders particularly depression and schizophrenia using epidemiological cohort studies, genetic analysis, and early-phase clinical trials. The key impetus for this work is to move immunotherapies closer to psychiatric practice through innovative translational research. He is also interested in life-course epidemiology of mental disorders, physical and psychiatric multimorbidity especially aetiology, early detection, and prevention of cardiometabolic disease in people with schiozophrenia and depression, and use of routine clinical data for health research.
Projects and supervisions
Research projects
CHECKPOINT: Finding immune and metabolic pathways to severe mental illness
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/04/2024 to 31/03/2029
8073 MRC IEU - Tim Larsen consumables
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
18/09/2023 to 01/10/2027
Integrative Epidemiology Unit
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/04/2023 to 31/03/2028
8073 MR/W014416/1 via Cardiff_Physical and mental health multimobidity across the lifespan
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/12/2021 to 30/11/2025
Psychosis Immune Mechanism Stratified Medicine Study (PIMS)
Principal Investigator
Managing organisational unit
Bristol Medical School (PHS)Dates
01/08/2021 to 31/05/2024
Thesis supervisions
Publications
Recent publications
27/01/2025Associations between IL-6 and trajectories of depressive symptoms across the life course
European Psychiatry
Childhood Allergy and Anxiety/Depression in Early Adulthood
Brain, Behavior, and Immunity
Depressive and Negative Symptoms in the Early and Established Stages of Schizophrenia: Integrating Structural Brain Alterations, Cognitive Performance, and Plasma Interleukin 6 Levels
Biological Psychiatry Global Open Science
Immunological Drivers and Potential Novel Drug Targets for Major Psychiatric, Neurodevelopmental, and Neurodegenerative Conditions
Molecular Psychiatry
Inflammation proteomic profiling of psychosis in young adults
Psychoneuroendocrinology