IEU Seminar: Thalia Eley
Room OS6, Second Floor, Oakfield House
MRC Integrative Epidemiology Unit (IEU) Seminar Series
Title: Big data approach to human fear conditioning: Combining smartphone and genomic data
Abstract:
We have developed a smartphone app (FLARe) which remotely delivers a fear conditioning task and which we are keen to share with collaborators worldwide. We are planning to make the tool open source and the data will be shared via a centralised database that pools anonymised data.
In this talk I will first describe the app, including how it has been validated, which aspects are flexible, and why it is suitable for different clinical and non-clinical populations and age-ranges. I will then present two large studies in which we will have begun collecting fear conditioning data using the app. The first of these is the Twins Early Development Study, a longitudinal study of over 7,000 pairs of twins born in England and Wales between 1994-1996. I will present initial fear conditioning data from 500 pairs of twins who have taken part in the study. Finally, I will present the Genetic Links to Anxiety and Depression (GLAD) Study, which we launched in September 2018. Over 20,000 individuals with lifetime diagnoses of an anxiety or depressive disorder, have already signed up for the study and will be invited to complete the FLARe app.
Biography:
All welcome