The following research publications relate to work conducted at TBRC.

• High spatial and temporal resolution Ca2+ imaging of myocardial strips from human, pig and rat' by Lyudmyla Borysova, Y. Y. Hanson Ng, Edward S. Wragg, Lillian E. Wallis, Emily Fay, Raimondo Ascione & Kim A. Dora. Nature Protocols

• Joanna R. Stasiak, Marta Serrani, Eugenia Biral, James Taylor, Francesco De Gaetano, Maria Laura Costantino, Vito D Bruno, Saadeh Suleiman, Raimondo Ascione, Geoff D. Moggridge (GD Moggridge and R Ascione are co-corresponding and co-senior authors). Design, Development, Testing at ISO standards and in-vivo feasibility study of a novel Polymeric Heart Valve Prosthesis. Biomaterials Science, 2020

• Hiran A. Prag1,2†, Anja V. Gruszczyk1,3†, Margaret M. Huang3, Timothy E. Beach3, Timothy Young2,4, Laura Tronci4, Efterpi Nikitopoulou4, Raimondo Ascione5, Anna Hadjihambi6, Michael J. Shattock7, Luc Pellerin6,8,9, Kourosh Saeb-Parsy3, Christian Frezza4, Andrew M. James1, Thomas Krieg2, Michael P. Murphy1, 2, and Dunja Aksentijević7,10* Mechanism of succinate efflux upon reperfusion of the ischemic heart. Cardiovascular Research 2020

• Watson SA, Scigliano M, Bardi I, Ascione R, Terracciano CM, Perbellini F. Preparation of viable adult ventricular myocardial slice from large and small mammals. Nature Protocols 2017; 12: 2623-2639.

• HC Gadeberg, RC Bond, CHT Kong, GP Chanoit, R Ascione, MB Cannell, AF James. Heterogeneity of T-Tubules in Pig Hearts. PloS one 11 (6), e0156862.

• The distribution, clearance, and brainstem toxicity of panobinostat administered by convection-enhanced delivery.  WGB Singleton, AS Bienemann, M Woolley, D Johnson, O Lewis, SS Gill (2018) Journal of Neurosurgery: Pediatrics 22 (3), 288-296 (2018)

• Reconstruction of the pulmonary artery by a novel biodegradable conduit engineered with perinatal stem cell-derived vascular smooth muscle cells enables physiological vascular growth in a large animal model of congenital heart disease. Ghorbel MT, Jia H, Swim MM, Iacobazzi D, Albertario A, Zebele C, Holopherne-Doran D, Hollander A, Madeddu P, Caputo M. Biomaterials. 2019 Oct;217:119284. doi: 10.1016/j.biomaterials.2019.119284. Epub 2019 Jun 20. PMID: 31255979

• Alvino VV, Kilcooley M, Thomas AC, Carrabba M, Fagnano M, Cathery W, Avolio E, Iacobazzi D, Ghorbel M, Caputo M, Madeddu P. In Vitro and In Vivo Preclinical Testing of Pericyte-Engineered Grafts for the Correction of Congenital Heart Defects. J Am Heart Assoc. 2020 Feb 18;9(4):e014214. doi:10.1161/JAHA.119.014214. Epub 2020 Feb 11.

• Formenti, F. Bommakanti, N. Chen, R. Cronin, J. McPeak, H. Holopherne-Doran, D. Hedenstierna, G. Hahn, CEW. Larsson, A. & Farmery, A,D. Respiratory oscillations in alveolar oxygen tension measured in arterial blood. Sci Rep 7, 7499 (2017).

• Iacobazzi D, Rapetto F, Albertario A, Swim MM, Narayan S, Skeffington K, Salih T, Alvino VV, Madeddu P, Ghorbel MT, Caputo M. Wharton’s Jelly-Mesenchymal Stem Cells-engineered conduit for paediatric translation in Heart Defect. Tissue Eng Part A. 2020 Jun 22. doi: 10.1089/ten.TEA.2020.0088. Ahead of print.

• Castellan RF, Vitiello M, Vidmar M, Johnstone S, Iacobazzi D, Mellis D, Cathcart B, Thomson AJ, Ruhrberg C, Caputo M, Newby DE, Gray GA, Baker AH, Caporali A, Meloni M. Mir-96 and miR-183 Differentially Regulate Neonatal and Adult Post-Infarct Neovascularisation. JCI Insight. 2020 Jun 16:134888. doi: 10.1172/jci.insight.134888.

• Albertario A, Swim MM, Ahmed AM, Iacobazzi D, Yeong M, Madeddu P, Ghorbel MT, Caputo M. Successful reconstruction of the right ventricular outflow tract by implantation of thymus stem cell engineered graft in growing swine.  JACC Basic Transl Sci. 2019 Jun 24;4(3):364-384. doi: 10.1016/j.jacbts.2019.02.001. eCollection 2019 Jun

• Swim MM, Albertario A, Iacobazzi D, Caputo M, Ghorbel MT. Amnion-based scaffold with enhanced strength and biocompatibility for in vivo vascular repair. Tissue Eng Part A. 2018 Oct 4. doi: 10.1089/ten.TEA.2018.0175.  

• Iacobazzi D, Swim M, Albertario A, Caputo M, Ghorbel MT. Thymus derived mesenchymal stem cells for tissue engineering clinical-grade cardiovascular grafts. Tissue Eng Part A. 2017 Oct 20. doi: 10.1089/ten.TEA.2017.0290.
  
  
• Bench and in-vivo feasibility testing in pig of a novel small diameter nanotextile arterial prosthesis
  John Joseph; Domenico Bruno; Nadiah Sulaiman; Alexander Ward; Tom Johnson; Helna Mary Baby; Shantikumar V Nair; Deepthy Menon; Sarah Jane George; Raimondo Ascione
  Journal of Nanobiotechnology