Publications

We highlight publications from BARC in key areas in the menus below. Recent particular highlights include:

[1] Gregson, F. et al. Comparing Aerosol Concentrations and Particle Size Distributions Generated by Singing, Speaking and Breathing. Aerosol Sci. Technol. 2021, 55, 681–691.

[2] Walker, J. S. et al. Accurate Representations of the Microphysical Processes Occurring during the Transport of Exhaled Aerosols and Droplets. ACS Cent. Sci. 2021, 7, 200–209. 

[3] Hamilton, F. et al. Aerosol Generating Procedures: Are They of Relevance for Transmission of SARS-CoV-2? Lancet Respir. Med. 2021, 9, 687–689.

[4] Song, Y. C. et al. Transient Cavity Dynamics and Divergence from the Stokes-Einstein Equation in Organic Aerosol. Chem. Sci. 2020, 11, 2999–3006.

[5] Bain et al., Surface-Area-to-Volume Ratio Determines Surface Tensions in Microscopic, Surfactant-Containing Droplets, ACS Central Science, 2023, 9, 2076–2083

[6] Bzdek, B. R.; Reid, J. P.; Cotterell, M. I. Open Questions on the Physical Properties of Aerosols. Comm. Chem. 2020, 3, 105.

Respiratory Aerosol

[1] Gregson, F. K. A.; Sheikh, S.; Archer, J.; Symons, H. E.; Walker, J. S.; Haddrell, A. E.; Orton, C. M.; Hamilton, F. W.; Brown, J. M.; Bzdek, B. R.; Reid, J. P. Analytical Challenges When Sampling and Characterising Exhaled Aerosol. Aerosol Sci. Technol. 2022. pdf

[2] Walker, J. S.; Archer, J.; Gregson, F. K. A.; Michel, S. E. S.; Bzdek, B. R.; Reid, J. P. Accurate Representations of the Microphysical Processes Occurring during the Transport of Exhaled Aerosols and Droplets. ACS Cent. Sci. 2021, 7 (1), 200–209. pdf

[3] McCarthy, L. P.; Orton, C. M.; et al. Aerosol and Droplet Generation from Performing with Woodwind and Brass Instruments. Aerosol Sci. Technol. 2021, 55, 1277–1287. pdf

[4] Gregson, F.; Watson, N. et al. Comparing Aerosol Concentrations and Particle Size Distributions Generated by Singing, Speaking and Breathing. Aerosol Sci. Technol. 2021, 55 (6), 681–691. pdf

Aerosol Generating Procedures

[1] Sheikh, S.; Hamilton, F. W. et al. Are Aerosols Generated during Lung Function Testing in Patients and Healthy Volunteers? Results from the AERATOR Study. Thorax 2022, thoraxjnl-2021-217671. pdf

[2] Hamilton, F. W.; Gregson, F. K. A. et al. Aerosol Emission from the Respiratory Tract: An Analysis of Aerosol Generation from Oxygen Delivery Systems. Thorax 2022, thoraxjnl-2021-217577. pdf

[3] Hamilton, F.; Arnold, D.; Bzdek, B. R.; Dodd, J.; Reid, J.; Maskell, N. Aerosol Generating Procedures: Are They of Relevance for Transmission of SARS-CoV-2? Lancet Respir. Med. 2021, 9 (7), 687–689. pdf

[4] Brown, J.; Gregson, F. K. A.; Shrimpton, A.; Cook, T. M.; Bzdek, B. R.; Reid, J. P.; Pickering, A. E. A Quantitative Evaluation of Aerosol Generation during Tracheal Intubation and Extubation. Anaesthesia 2021, 76, 174–181. pdf

Hygroscopicity 

[1] Marsh, A.; Miles, R. E. H.; Rovelli, G.; Cowling, A. G.; Nandy, L.; Dutcher, C. S.; Reid, J. P. Influence of Organic Compound Functionality on Aerosol Hygroscopicity: Dicarboxylic Acids, Alkyl-Substituents, Sugars and Amino Acids. Atmos. Chem. Phys. 2017, 17, 5583–5599. pdf

[2] Marsh, A.; Rovelli, G.; Song, Y.-C.; Pereira, K. L.; Willoughby, R. E.; Bzdek, B. R.; Hamilton, J.; Orr-Ewing, A.; Topping, D. O.; Reid, J. P. Accurate Representations of the Physicochemical Properties of Atmospheric Aerosols: When Are Laboratory Measurements of Value? Faraday Discuss. 2017, 200, 639–661. pdf

Viscosity and Phase

[1] Reid, J. P.; Bertram, A. K.; Topping, D. O.; Laskin, A.; Martin, S. T.; Petters, M. D.; Pope, F. D.; Rovelli, G. The Viscosity of Atmospherically Relevant Organic Particles. Nat. Commun. 2018, 9 (1), 956. pdf

[2] Price, H. C.; Mattsson, J.; et al. Water Diffusion in Atmospherically Relevant α-Pinene Secondary Organic Material. Chem. Sci. 2015, 6, 4876–4883. pdf

[3] Lienhard, D. M.; Huisman, A. J.; et al. Viscous Organic Aerosol Particles in the Upper Troposphere : Diffusivity-Controlled Water Uptake and Ice Nucleation ? Atmos. Chem. Phys. 2015, 15, 13599–13613. pdf

Mass Accommodation

[1] Davies, J. F.; Miles, R. E. H.; Haddrell, A. E.; Reid, J. P. Temperature Dependence of the Vapor Pressure and Evaporation Coefficient of Supercooled Water. J. Geophys. Res. - Atmos. 2014, 119, 10,931–10,940. pdf

[2] Davies, J. F.; Miles, R. E. H.; Haddrell, A. E.; Reid, J. P. Influence of Organic Films on the Evaporation and Condensation of Water in Aerosol. Proc. Natl. Acad. Sci. U.S.A. 2013, 110 (22), 8807–8812. pdf

Volatility

[1] Petters, S. S.; Hilditch, T. G.; Tomaz, S.; Miles, R. E. H.; Reid, J. P.; Turpin, B. J. Volatility Change during Droplet Evaporation of Pyruvic Acid. ACS Earth Sp. Chem. 2020, 4 (5), 741–749. pdf

Inhaled Aerosols in Drug Delivery

[1] Ordoubadi, M.; Gregson, F. K. A.; et al. Trileucine as a Dispersibility Enhancer of Spray-Dried Inhalable Microparticles. J. Control. Release 2021, 336, 522–536. pdf

[2] Legh-Land, V.; Haddrell, A. E.; Lewis, D.; Murnane, D.; Reid, J. P. Water Uptake by Evaporating PMDI Aerosol Prior to Inhalation Affects Both Regional and Total Deposition in the Respiratory System. Pharmaceutics 2021, 13, 941. pdf

[3] Haddrell, A. E.; Lewis, D.; Church, T.; Vehring, R.; Murnane, D.; Reid, J. P. Pulmonary Aerosol Delivery and the Importance of Growth Dynamics. Ther. Deliv. 2017, 8, 1051–1061. pdf

[4] Farkas, Á.; Lewis, D.; Church, T.; Tweedie, A.; Mason, F.; Haddrell, A. E.; Reid, J. P.; Horváth, A.; Balásházy, I. Experimental and Computational Study of the Effect of Breath-Actuated Mechanism Built in the NEXThaler® Dry Powder Inhaler. Int. J. Pharm. 2017, 533 (1), 225–235. pdf

[5] Haddrell, A. E.; Davies, J. F.; Miles, R. E. H.; Reid, J. P.; Dailey, L. A.; Murnane, D. Dynamics of Aerosol Size during Inhalation: Hygroscopic Growth of Commercial Nebulizer Formulations. Int. J. Pharm. 2014, 463 (1), 50–61. pdf

Biological Aerosol

[1] Oswin, H.; Haddrell, A.; et al. Measuring Stability of Virus in Aerosols under Varying Environmental Conditions. Aerosol Sci. Technol. 2021, 55 (12), 1315–1320. pdf

[2] Fernandez, M. O.; Thomas, R. J.; Oswin, H.; Haddrell, A. E.; Reid, J. P. Transformative Approach to Investigate the Microphysical Factors Influencing the Airborne Transmission of Pathogens. Appl. Environ. Microbiol. 2020, 86 (23), 1–13. pdf

[3] Fernandez, M. O.; Thomas, R. J.; Garton, N. J.; Hudson, A.; Haddrell, A.; Reid, J. P. Assessing the Airborne Survival of Bacteria in Populations of Aerosol Droplets with a Novel Technology. J. R. Soc. Interface 2019, 16 (150), 20180779. pdf

Whole Lung Models of Deposition in the Lung

[1] Haddrell, A. E.; Davies, J. F.; Reid, J. P. Dynamics of Particle Size on Inhalation of Environmental Aerosol and Impact on Deposition Fraction. Environ. Sci. Technol. 2015, 49, 14512−14521. pdf

Single Particle Cavity Ringdown Measurements

[1] Valenzuela, A.; Chu, F.; et al. Optical Interrogation of Single Levitated Droplets in a Linear Quadrupole Trap by Cavity Ring-Down Spectroscopy. J. Phys. Chem. A 2021, 125 (1), 394–405. pdf

[2] Mason, B.J.; Cotterell, M.I.; Preston, T.C.; Orr-Ewing, A.J.; Reid, J.P. Direct Measurements of the Optical Cross Sections and Refractive Indices of Individual Volatile and Hygroscopic Aerosol Particles. J. Phys. Chem. A 2015, 119, 5701–5713. pdf

[3] Cotterell, M.I.; Mason, B.J.; Preston, T.C.; Orr-Ewing, A.J.; Reid, J.P. Optical Extinction Efficiency Measurements on Fine and Accumulation Mode Aerosol Using Single Particle Cavity Ring-Down Spectroscopy. Phys. Chem. Chem. Phys. 2015, 17 (24), 15843–15856. pdf

Accuracy and Representation of Optical Properties for Atmospheric Aerosols

[1] Valenzuela, A.; Reid, J. P.; Bzdek, B. R.; Orr-Ewing, A. J. Accuracy Required in Measurements of Refractive Index and Hygroscopic Response to Reduce Uncertainties in Estimates of Aerosol Radiative Forcing Efficiency. J. Geophys. Res. Atmos. 2018, 123, 6469–6486. pdf

[2] Cotterell, M. I.; Willoughby, R. E.; Bzdek, B. R.; Orr-Ewing, A. J.; Reid, J. P. A Complete Parameterisation of the Relative Humidity and Wavelength Dependence of the Refractive Index of Hygroscopic Inorganic Aerosol Particles. Atmos. Chem. Phys. 2017, 17 (16), 9837–9851. pdf

[3] Cai, C.; Marsh, A.; Zhang, Y.-H.; Reid, J. P. Group Contribution Approach to Predict the Refractive Index of Pure Organic Components in Ambient Organic Aerosol. Environ. Sci. Technol. 2017, 51 (17), 9683−9690.  pdf

[4] Cotterell, M. I.; Preston, T. C.; Orr-Ewing, A. J.; Reid, J. P. Assessing the Accuracy of Complex Refractive Index Retrievals from Single Aerosol Particle Cavity Ring-Down Spectroscopy. Aerosol Sci. Technol. 2016, 50 (10), 1077–1095. pdf

Characterising Particle Morphology and Size

[1] Haddrell, A.; Rovelli, G.; Lewis, D.; Church, T.; Reid, J. Identifying Time-Dependent Changes in the Morphology of an Individual Aerosol Particle from Its Light Scattering Pattern. Aerosol Sci. Technol. 2019, 53 (11), 1334–1351. pdf

[2] Preston, T. C.; Reid, J. P. Determining the Size and Refractive Index of Microspheres Using the Mode Assignments from Mie Resonances. J. Opt. Soc. Am. A 2015, 32 (11), 2210. pdf

Surface Tension Measurement Techniques

[1] Bzdek, B. R.; Power, R. M.; Simpson, S. H.; Reid, J. P.; Royall, C. P. Precise, Contactless Measurements of the Surface Tension of Picolitre Aerosol Droplets. Chem. Sci. 2016, 7, 274–285. pdf

[2] Bzdek, B. R.; Collard, L.; Sprittles, J. E.; Hudson, A. J.; Reid, J. P. Dynamic Measurements and Simulations of Airborne Picolitre-Droplet Coalescence in Holographic Optical Tweezers. J. Chem. Phys. 2016, 145, 054502. pdf

Surfactant and Water Soluble Organic Containing Droplets

[1] Miles, R. E. H.; Glerum, M. W. J.; Boyer, H. C.; Walker, J. S.; Dutcher, C. S.; Bzdek, B. R. Surface Tensions of Picoliter Droplets with Sub-Millisecond Surface Age. J. Phys. Chem. A 2019, 123 (13), 3021–3029. pdf

[2] Bzdek, B. R.; Reid, J. P.; Malila, J.; Prisle, N. L. The Surface Tension of Surfactant-Containing, Finite Volume Droplets. Proc. Natl. Acad. Sci. U. S. A. 2020, 117 (15), 8335–8343. pdf

[3] Boyer, H. C.; Bzdek, B. R.; Reid, J. P.; Dutcher, C. S. A Statistical Thermodynamic Model for Surface Tension of Organic and Inorganic Aqueous Mixtures. J. Phys. Chem. A 2017, 121, 198–205. pdf

Liquid-Liquid Phase Separation 

[1] Reid, J. P.; Dennis-Smither, B. J.; Kwamena, N.-O. A.; Miles, R. E. H.; Hanford, K. L.; Homer, C. J. The Morphology of Aerosol Particles Consisting of Hydrophobic and Hydrophilic Phases: Hydrocarbons, Alcohols and Fatty Acids as the Hydrophobic Component. Phys. Chem. Chem. Phys. 2011, 13 (34), 15559–15572. pdf

[2] Kwamena, N.-O. A.; Buajarern, J.; Reid, J. P. Equilibrium Morphology of Mixed Organic/Inorganic/Aqueous Aerosol Droplets: Investigating the Effect of Relative Humidity and Surfactants. J. Phys. Chem. A 2010, 114 (18), 5787–5795. pdf

[3] Buajarern, J.; Mitchem, L.; Reid, J. P. Characterizing Multiphase Organic/Inorganic/Aqueous Aerosol Droplets. J. Phys. Chem. A 2007, 111 (37), 9054–9061. pdf

Particle Viscosity

[1] Rovelli, G.; Song, Y. C.; MacLean, A. M.; Topping, D. O.; Bertram, A. K.; Reid, J. P. Comparison of Approaches for Measuring and Predicting the Viscosity of Ternary Component Aerosol Particles. Anal. Chem. 2019, 91 (8), 5074–5082. pdf

[2] Reid, J. P.; Bertram, A. K.; Topping, D. O.; Laskin, A.; Martin, S. T.; Petters, M. D.; Pope, F. D.; Rovelli, G. The Viscosity of Atmospherically Relevant Organic Particles. Nat. Commun. 2018, 9 (1), 956. pdf

[3] Power, R. M.; Simpson, S. H.; Reid, J. P.; Hudson, A. J. The Transition from Liquid to Solid-Like Behaviour in Ultrahigh Viscosity Aerosol Particles. Chem. Sci. 2013, 4 (6), 2597–2604. pdf

[4] Rothfuss, N. E.; Marsh, A.; Rovelli, G.; Petters, M. D.; Reid, J. P. Condensation Kinetics of Water on Amorphous Aerosol Particles. J. Phys. Chem. Lett. 2018, 9 (13), 3708−3713. pdf

[5] Song, Y. C.; Haddrell, A. E.; Bzdek, B. R.; Reid, J. P.; Bannan, T.; Topping, D. O.; Percival, C. J.; Cai, C. Measurements and Predictions of Binary Component Aerosol Particle Viscosity. J. Phys. Chem. A 2016, 120, 8123–8137. pdf

Molecluar Diffusion and Stokes Einstein Equation

[1] Ingram, S.; Rovelli, G.; Song, Y.-C.; Topping, D.; Dutcher, C. S.; Liu, S.; Nandy, L.; Shiraiwa, M.; Reid, J. P. Accurate Prediction of Organic Aerosol Evaporation Using Kinetic Multilayer Modeling and the Stokes–Einstein Equation. J. Phys. Chem. A 2021, 125, 3444–3456. pdf

[2] Song, Y. C.; Ingram, S.; Arbon, R. E.; Topping, D. O.; Glowacki, D. R.; Reid, J. P. Transient Cavity Dynamics and Divergence from the Stokes-Einstein Equation in Organic Aerosol. Chem. Sci. 2020, 11, 2999–3006. pdf

[3] Evoy, E.; Maclean, A. M.; et al. Predictions of Diffusion Rates of Large Organic Molecules in Secondary Organic Aerosols Using the Stokes–Einstein and Fractional Stokes–Einstein Relations. Atmos. Chem. Phys. 2019, 19, 10073–10085. pdf

Viscosity and Reactivity

[1] Marshall, F. H.; Miles, R. E. H.; Song, Y.-C.; Ohm, P. B.; Power, R. M.; Reid, J. P.; Dutcher, C. S. Diffusion and Reactivity in Ultraviscous Aerosol and the Correlation with Particle Viscosity. Chem. Sci. 2016, 7 (2), 1298–1308. pdf

Evaporation and Crystallisation

[1] Hardy, D. A.; Archer, J.; Lemaitre, P.; Vehring, R.; Reid, J. P.; Walker, J. S. High Time Resolution Measurements of Droplet Evaporation Kinetics and Particle Crystallisation. Phys. Chem. Chem. Phys. 2021. pdf

[2] Gregson, F. K. A.; Robinson, J. F.; Miles, R. E. H.; Royall, C. P.; Reid, J. P. Drying and Crystallization of Evaporating Sodium Nitrate Aerosol Droplets. J. Phys. Chem. B 2020, 124, 6024–6036. pdf

[3] Gregson, F. K. A.; Ordoubadi, M.; Miles, R. E. H.; Haddrell, A.; Barona, D.; Lewis, D.; Church, T.; Vehring, R.; Reid, J. P. Studies of Competing Evaporation Rates of Multiple Volatile Components from a Single Binary-Component Aerosol Droplet. Phys. Chem. Chem. Phys. 2019, 21, 9709–9719. pdf

[4] Gregson, F. K. A.; Robinson, J. F.; Miles, R. E. H.; Royall, C. P.; Reid, J. P. Drying Kinetics of Salt Solution Droplets: Water Evaporation Rates and Crystallization. J. Phys. Chem. B 2019, 123 (1), 266–276. pdf

Colloidal Suspensions

[1] Archer, J.; Walker, J.; Gregson, F. K. A.; Hardy, D. A.; Reid, J. P. Drying Kinetics and Particle Formation from Dilute Colloidal Suspensions in Aerosol Droplets. Langmuir 2020, 36, 12481–12493. pdf

Informing Spray Drying

[1] Ordoubadi, M.; Gregson, F. K. A.; Wang, H.; Nicholas, M.; Gracin, S.; Lechuga-Ballesteros, D.; Reid, J. P.; Finlay, W. H.; Vehring, R. On the Particle Formation of Leucine in Spray Drying of Inhalable Microparticles. Int. J. Pharm. 2021, 592, 120102. pdf

[2] Ordoubadi, M.; Gregson, F. K. A.; Wang, H.; Carrigy, N. B.; Nicholas, M.; Gracin, S.; Lechuga-Ballesteros, D.; Reid, J. P.; Finlay, W. H.; Vehring, R. Trileucine as a Dispersibility Enhancer of Spray-Dried Inhalable Microparticles. J. Control. Release 2021, 336, 522–536. pdf

[3] Ordoubadi, M.; Gregson, F. K. A.; Melhem, O.; Barona, D.; Miles, R. E. H.; D’Sa, D.; Gracin, S.; Lechuga-Ballesteros, D.; Reid, J. P.; Finlay, W. H.; Vehring, R. Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics. Pharm. Res. 2019, 36 (7), 10.1007/s11095-019-2630–2637. pdf