World's first research programme to identify scarring gene launched26 November 2020A world-leading £1.5 million research programme that aims to achieve scar free healing within a generation has been launched today [26 November] by The Scar Free Foundation, the only medical research charity which focuses solely on scarring. The five-year research study led by the University of Bristol will identify the gene(s) that causes scarring and inform future treatments
Neuropilin-1 drives SARS-CoV-2 infectivity, finds breakthrough study20 October 2020In a major breakthrough an international team of scientists, led by the University of Bristol, has potentially identified what makes SARS-CoV-2 highly infectious and able to spread rapidly in human cells. The findings, published in Science today [20 October] describe how the virus’s ability to infect human cells can be reduced by inhibitors that block a newly discovered interaction between virus and host, demonstrating a potential anti-viral treatment.
Discovery of a druggable pocket in the SARS-CoV-2 Spike protein could stop virus in its tracks21 September 2020A druggable pocket in the SARS-CoV-2 Spike protein that could be used to stop the virus from infecting human cells has been discovered by an international team of scientists led by the University of Bristol. The researchers say their findings, published today [21 September] in the journal Science, are a potential 'game changer' in defeating the current pandemic and add that small molecule anti-viral drugs developed to target the pocket they discovered could help eliminate COVID-19.
New drug formulation could treat Candida infections28 April 2020With antimicrobial resistance (AMR) increasing around the world, new research led by the University of Bristol has shown a new drug formulation could possibly be used in antifungal treatments against Candida infections.
Catalytic protocells get zingy8 January 2020Artificial cells capable of oxygen gas production and chemical signalling have been prepared using a combination of synthetic and biological catalysts through an international collaboration between the University of Bristol and the University of Padua in Italy.