News in 2015
- Winning entries for Art of Science 2015 competition 30 November 2015 Wolfson Bioimaging Facility users were yet again successful in this year’s Art of Science competition. Prize-winning images were submitted by Ilona Aylott (confocal), Jenna Cash (multiphoton) and Catherine Twomey (Confocal).
- First steps towards new therapy for diseases caused by defective anion transport 5 November 2015 Research by a team at the University of Bristol has taken the first steps towards new treatments for inherited diseases such as cystic fibrosis; one form of Bartter’s syndrome (severe salt loss from the kidney); and two forms of myotonia (muscle stiffness), which are linked to defective movement of anions, such as chloride, across cell membranes.
- Major new investment in informatics service support for health and biomedical research at the University of Bristol 27 October 2015 The Elizabeth Blackwell Institute, through its Wellcome Trust ISSF Award, is delighted to announce that it will be investing £150,000 in three new posts that will be openly available to help support all health and biomedical researchers across the University in their informatics needs.
- Light Microscopy Workshop 24 September 2015
- Mechanistic links between inflammation and cancer grab EMBO J front page. 23 September 2015
- Ballooning platelets and the future of anti-thrombotic drugs 7 September 2015 Membrane ballooning in platelets during the blood-clotting process is driven by a coordinated system of salt and water entry which may be modified pharmacologically, a new study from the University of Bristol has found. The research could ultimately lead to the development of better ‘blood-thinning’ drugs for patients who experience complications with or are resistant to existing antiplatelet drugs such as aspirin.
- Endothelial trafficking study is first Bristol STED publication 2 September 2015 A new paper exploring cytoskeleton regulation and trafficking in endothelial cells is the first paper to include images obtained with the Wolfson Bioimaging Facility’s super-resolution microscope
- Watching how signalling regulates T cell activation 5 August 2015 By combining visualisation of the subcellular distributions of more than 60 signalling intermediates with microscopy across size scales Christoph Wülfing’s group have gained insight into how T cells regulate their activation
- Automated live cell imaging with IncuCyte ZOOM 17 July 2015 The latest addition to the Wolfson Bioimaging Facility is a dedicated live cell imaging system offering automated image acquisition and analysis with ‘high throughput’ capabilities.
- New dual-mode imaging option on Leica SPE system 14 July 2015 Addition of a CCD camera has converted the Wolfson Bioimaging Facility’s Leica SPE system into its first dual-mode (confocal/widefield) imaging system.
- Ultrasound accelerates skin healing – especially for diabetics and the elderly 14 July 2015 Healing times for skin ulcers and bedsores can be reduced by a third with the use of low-intensity ultrasound, scientists from the Universities of Sheffield and Bristol have found.
- Tissue ‘scaffold’ technology could help rebuild large organs 24 June 2015 Scientists have developed a new tissue ‘scaffold’ technology that could one day enable the engineering of large organs. Research led by the Universities of Bristol and Liverpool has shown that it is possible to combine cells with a special scaffold to produce living tissue in the laboratory. It is hoped this can then be implanted into patients as a way of replacing diseased parts of the body.
- Quantitative microscopy reveals mechanisms of Rac1 trafficking 20 May 2015 A new paper from Mark Bass’s group is the first to include data acquired with the Wolfson Bioimaging Facility’s Widefield-1 system since it underwent extensive upgrading.
- Leica SP8 Digital Light Sheet Workshop: 13th and 14th May 2015 27 April 2015 The University of Bristol’s Wolfson Bioimaging Facility in collaboration with Leica Microsystems is hosting one of the first demonstrations of the DLS light sheet microscope in the UK. This technique allows fluorescence imaging of model organisms, tissues and cell spheroids at high speed and with minimal photodamage.
- Three advanced fluorescence techniques in one microscope system 24 April 2015 The University of Bristol’s Wolfson Bioimaging Facility has installed a state-of-the-art microscope system offering researchers three advanced techniques to study the localisation and dynamics of fluorescent molecules inside cells.
