The Dementia Research Group conducts laboratory-based (preclinical) research that translates into clinical research in dementia.

We use molecular genetic, biochemical and neuropathological approaches on human tissue and in experimental cell-based systems to increase our understanding of the underlying causes and pathological mechanisms of dementia.

Some of this research has been extended and the findings tested in human patients and normal volunteers, in cognitive, neuroimaging and molecular epidemiological studies conducted in collaboration with our colleagues in the ReMeMBr Group and the Bristol Medical School: Population Health Sciences.

Our main aim is to translate our laboratory-based findings into applications that benefit patients with dementia.

Our laboratory-based research is almost exclusively undertaken in the Learning & Research building, at Southmead Hospital, Bristol.

This also houses the Human Tissue Authority-licensed South West Dementia Brain Bank.

The clinical research of the ReMeMBr Group is conducted in the adjacent Brain Centre.

The Dementia Research Group is part of the University of Bristol's Institute of Clinical Neurosciences.

It is also a member of the Bristol and Bath Alzheimer's Research UK Network Centre, one of the main partners in the Brains for Dementia Research (BDR) Initiative, a member of the GW4 Aging and Dementia (GW4AD) Consortium, and a member of the European Alzheimer's Disease Consortium (EADC).