Directory of Experts
Details for Dr Fiona Holmes
| Personal details | |
| Name | Dr Fiona Holmes |
| Job title | Teaching Fellow in Clinical Sciences |
| Department | Bristol Medical School (THS) University of Bristol |
| Contact details | This expert can be contacted via the University of Bristol Public Relations
Office. To help us deal with your request, please mention the Directory of Experts when contacting the Public Relations Office. work+44 (0)117 331 8092 email: public-relations@bristol.ac.uk |
| Qualifications | B.Sc., Ph.D. (Kent) |
| Professional details | |
| Keywords | neuropathic pain dorsal root ganglia sensory neurons glia chemokines galanin |
| Areas of expertise | My main area of interest is to further understand the pathophysiology of neuropathic pain by studying the roles of factors that are differentially regulated in the dorsal root ganglion (DRG) following peripheral nerve damage. After injury to peripheral nerves there are changes in the expression of many factors - both in sensory neurons and non-neuronal cells (e.g. satellite glia and macrophages), that may contribute to the adaptive or maladaptive responses of the peripheral nervous sytem to injury, by modulating neuronal survival, regeneration and pain. I am particularly interested in the roles of chemokines, specifically CX3CL1, and the neuropeptide galanin. Much of my work is done in close collaboration with Prof David Wynick. |