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Details for Professor David Stephens

Personal details
Name Professor David Stephens
Job title Professor of Cell Biology
Department School of Biochemistry University of Bristol
Personal web page http://www.bristol.ac.uk/biochemistry/stephens/index.html
Contact details This expert can be contacted via the University of Bristol Public Relations Office.

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work+44 (0)117 331 8092
email:
Qualifications B.Sc., Ph.D.(Lond.)
Professional details
Membership of professional bodies British Society for Cell Biology
American Society for Cel Biology
Fellow of the Royal Microscopical Society
Keywords membrane traffic
mammalian cells
bioimaging
molecular mechanisms
secretion
microscopy
cell imaging
motor proteins
Areas of expertise The principle focus of our current work is the function of the early secretory pathway in mammalian cells. We are seeking to develop an understanding of the way in which the cell moves vital components that go to build up the extracellular matrix as well as how cells assemble important structures and organize together in 3D to form tissues. In addition, we are continuing our work on the role of microtubule motor proteins in membrane traffic with a particular emphasis on ER-to-Golgi transport. The lab specializes in the analysis of membrane traffic in mammalian cells using advanced light microscopy techniques, in particular, the imaging of living cells. Our work includes developing imaging technologies and integrating model systems including 3D cultures and zebrafish to develop our research.