Directory of Experts
Details for Dr Karim Malik
| Personal details | |
| Name | Dr Karim Malik |
| Job title | Reader in Epigenetics |
| Department | School of Cellular and Molecular Medicine University of Bristol |
| Contact details | This expert can be contacted via the University of Bristol Public Relations
Office. To help us deal with your request, please mention the Directory of Experts when contacting the Public Relations Office. work+44 (0)117 331 8092 email: public-relations@bristol.ac.uk |
| Qualifications | B.Sc.(Sur.), Ph.D.(Cantab.) |
| Professional details | |
| Keywords | Wilms' tumour eukaryotic gene expression cancer epigenetics genetics non-coding RNA |
| Areas of expertise | Current Research Cancer epigenetics - We are conducting genome-wide methylation screening using microarrays in order to assess epigenetic lesions in human cancers and the downstream consequences of gene deregulation. Regulation and cellular functions of the Wilms' tumour suppressor gene, WT1 - Identification of an antisense WT1 promoter has led us to propose novel control mechanisms for eukaryotic gene expression involving antisense RNAs and silencer elements. We also identified a novel WT1 form whose functions are being invesigated. |